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Page 1
Melatonin Reduces NLRP3 Inflammasome Activation by Increasing α7 nAChR-Mediated Autophagic Flux.
Farré-Alins V, Narros-Fernández P, Palomino-Antolín A, Decouty-Pérez C, Lopez-Rodriguez AB, Parada E, Muñoz-Montero A, Gómez-Rangel V, López-Muñoz F, Ramos E, González-Rodríguez Á, Gandía L, Romero A, Egea J. Farré-Alins V, et al. Among authors: egea j. Antioxidants (Basel). 2020 Dec 18;9(12):1299. doi: 10.3390/antiox9121299. Antioxidants (Basel). 2020. PMID: 33353046 Free PMC article.
TLR4 pathway impairs synaptic number and cerebrovascular functions through astrocyte activation following traumatic brain injury.
Rosa JM, Farré-Alins V, Ortega MC, Navarrete M, Lopez-Rodriguez AB, Palomino-Antolín A, Fernández-López E, Vila-Del Sol V, Decouty C, Narros-Fernández P, Clemente D, Egea J. Rosa JM, et al. Among authors: egea j. Br J Pharmacol. 2021 Sep;178(17):3395-3413. doi: 10.1111/bph.15488. Epub 2021 Jun 1. Br J Pharmacol. 2021. PMID: 33830504 Free PMC article.
Serum Amyloid A1/Toll-Like Receptor-4 Axis, an Important Link between Inflammation and Outcome of TBI Patients.
Farré-Alins V, Palomino-Antolín A, Narros-Fernández P, Lopez-Rodriguez AB, Decouty-Perez C, Muñoz-Montero A, Zamorano-Fernández J, Mansilla-Fernández B, Giner-García J, García-Feijoo P, Sáez-Alegre M, Palpán-Flores AJ, Roda-Frade JM, Carabias CS, Rosa JM, Civantos-Martín B, Yus-Teruel S, Gandía L, Lagares A, Hernández-García BJ, Egea J. Farré-Alins V, et al. Among authors: egea j. Biomedicines. 2021 May 25;9(6):599. doi: 10.3390/biomedicines9060599. Biomedicines. 2021. PMID: 34070533 Free PMC article.
Time-dependent dual effect of NLRP3 inflammasome in brain ischaemia.
Palomino-Antolin A, Narros-Fernández P, Farré-Alins V, Sevilla-Montero J, Decouty-Pérez C, Lopez-Rodriguez AB, Fernández N, Monge L, Casas AI, Calzada MJ, Egea J. Palomino-Antolin A, et al. Among authors: egea j. Br J Pharmacol. 2022 Apr;179(7):1395-1410. doi: 10.1111/bph.15732. Epub 2022 Feb 5. Br J Pharmacol. 2022. PMID: 34773639 Free article.
Synthesis and Pharmacological Evaluation of New N-Sulfonylureas as NLRP3 Inflammasome Inhibitors: Identification of a Hit Compound to Treat Gout.
Narros-Fernández P, Chioua M, Petcu SA, Diez-Iriepa D, Cerrada-Gálvez L, Decouty-Pérez C, Palomino-Antolín A, Ramos E, Farré-Alins V, López-Rodríguez AB, Romero A, Marco-Contelles J, Egea J. Narros-Fernández P, et al. Among authors: egea j. J Med Chem. 2022 Apr 28;65(8):6250-6260. doi: 10.1021/acs.jmedchem.2c00149. Epub 2022 Apr 11. J Med Chem. 2022. PMID: 35403430
Redox Regulation of Microglial Inflammatory Response: Fine Control of NLRP3 Inflammasome through Nrf2 and NOX4.
Palomino-Antolín A, Decouty-Pérez C, Farré-Alins V, Narros-Fernández P, Lopez-Rodriguez AB, Álvarez-Rubal M, Valencia I, López-Muñoz F, Ramos E, Cuadrado A, Casas AI, Romero A, Egea J. Palomino-Antolín A, et al. Among authors: egea j. Antioxidants (Basel). 2023 Sep 7;12(9):1729. doi: 10.3390/antiox12091729. Antioxidants (Basel). 2023. PMID: 37760032 Free PMC article.
Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia.
Hernansanz-Agustín P, Ramos E, Navarro E, Parada E, Sánchez-López N, Peláez-Aguado L, Cabrera-García JD, Tello D, Buendia I, Marina A, Egea J, López MG, Bogdanova A, Martínez-Ruiz A. Hernansanz-Agustín P, et al. Among authors: egea j. Redox Biol. 2017 Aug;12:1040-1051. doi: 10.1016/j.redox.2017.04.025. Epub 2017 Apr 21. Redox Biol. 2017. PMID: 28511347 Free PMC article.
Na+ controls hypoxic signalling by the mitochondrial respiratory chain.
Hernansanz-Agustín P, Choya-Foces C, Carregal-Romero S, Ramos E, Oliva T, Villa-Piña T, Moreno L, Izquierdo-Álvarez A, Cabrera-García JD, Cortés A, Lechuga-Vieco AV, Jadiya P, Navarro E, Parada E, Palomino-Antolín A, Tello D, Acín-Pérez R, Rodríguez-Aguilera JC, Navas P, Cogolludo Á, López-Montero I, Martínez-Del-Pozo Á, Egea J, López MG, Elrod JW, Ruíz-Cabello J, Bogdanova A, Enríquez JA, Martínez-Ruiz A. Hernansanz-Agustín P, et al. Among authors: egea j. Nature. 2020 Oct;586(7828):287-291. doi: 10.1038/s41586-020-2551-y. Epub 2020 Jul 29. Nature. 2020. PMID: 32728214 Free PMC article.
278 results