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Enhanced anti-tumor efficacy of checkpoint inhibitors in combination with the histone deacetylase inhibitor Belinostat in a murine hepatocellular carcinoma model.
Llopiz D, Ruiz M, Villanueva L, Iglesias T, Silva L, Egea J, Lasarte JJ, Pivette P, Trochon-Joseph V, Vasseur B, Dixon G, Sangro B, Sarobe P. Llopiz D, et al. Among authors: egea j. Cancer Immunol Immunother. 2019 Mar;68(3):379-393. doi: 10.1007/s00262-018-2283-0. Epub 2018 Dec 13. Cancer Immunol Immunother. 2019. PMID: 30547218 Free PMC article.
Preclinical evaluation of a synthetic peptide vaccine against SARS-CoV-2 inducing multiepitopic and cross-reactive humoral neutralizing and cellular CD4 and CD8 responses.
Aparicio B, Casares N, Egea J, Ruiz M, Llopiz D, Maestro S, Olagüe C, González-Aseguinolaza G, Smerdou C, López-Díaz de Cerio A, Inogés S, Prósper F, Yuste JR, Carmona-Torre F, Reina G, Lasarte JJ, Sarobe P. Aparicio B, et al. Among authors: egea j. Emerg Microbes Infect. 2021 Dec;10(1):1931-1946. doi: 10.1080/22221751.2021.1978823. Emerg Microbes Infect. 2021. PMID: 34538222 Free PMC article.
Neoantigens as potential vaccines in hepatocellular carcinoma.
Repáraz D, Ruiz M, Llopiz D, Silva L, Vercher E, Aparicio B, Egea J, Tamayo-Uria I, Hervás-Stubbs S, García-Balduz J, Castro C, Iñarrairaegui M, Tagliamonte M, Mauriello A, Cavalluzzo B, Buonaguro L, Rohrer C, Heim K, Tauber C, Hofmann M, Thimme R, Sangro B, Sarobe P. Repáraz D, et al. Among authors: egea j. J Immunother Cancer. 2022 Feb;10(2):e003978. doi: 10.1136/jitc-2021-003978. J Immunother Cancer. 2022. PMID: 35193931 Free PMC article.
Gemcitabine-mediated depletion of immunosuppressive dendritic cells enhances the efficacy of therapeutic vaccination.
Repáraz D, Ruiz M, Silva L, Aparicio B, Egea J, Guruceaga E, Ajona D, Senent Y, Conde E, Navarro F, Barace S, Alignani D, Hervás-Stubbs S, Lasarte JJ, Llopiz D, Sarobe P. Repáraz D, et al. Among authors: egea j. Front Immunol. 2022 Oct 10;13:991311. doi: 10.3389/fimmu.2022.991311. eCollection 2022. Front Immunol. 2022. PMID: 36300124 Free PMC article.
A Therapeutically Actionable Protumoral Axis of Cytokines Involving IL-8, TNFα, and IL-1β.
Olivera I, Sanz-Pamplona R, Bolaños E, Rodriguez I, Etxeberria I, Cirella A, Egea J, Garasa S, Migueliz I, Eguren-Santamaria I, Sanmamed MF, Glez-Vaz J, Azpilikueta A, Alvarez M, Ochoa MC, Malacrida B, Propper D, de Andrea CE, Berraondo P, Balkwill FR, Teijeira Á, Melero I. Olivera I, et al. Among authors: egea j. Cancer Discov. 2022 Sep 2;12(9):2140-2157. doi: 10.1158/2159-8290.CD-21-1115. Cancer Discov. 2022. PMID: 35771565
Depletion of Conventional Type-1 Dendritic Cells in Established Tumors Suppresses Immunotherapy Efficacy.
Teijeira A, Garasa S, Luri-Rey C, de Andrea C, Gato M, Molina C, Kaisho T, Cirella A, Azpilikueta A, Wculek SK, Egea J, Olivera I, Rodriguez I, Rouzaut A, Verkhusha V, Valencia K, Sancho D, Berraondo P, Melero I. Teijeira A, et al. Among authors: egea j. Cancer Res. 2022 Dec 2;82(23):4373-4385. doi: 10.1158/0008-5472.CAN-22-1046. Cancer Res. 2022. PMID: 36130020
278 results