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In Vitro and In Silico ADME-Tox Profiling and Safety Significance of Multifunctional Monoamine Oxidase Inhibitors Targeting Neurodegenerative Diseases.
Więckowska A, Szałaj N, Góral I, Bucki A, Latacz G, Kiec-Kononowicz K, Bautista-Aguilera ÒM, Romero A, Ramos E, Egea J, Farré Alíns V, González-Rodríguez Á, López-Muñoz F, Chioua M, Marco-Contelles J. Więckowska A, et al. Among authors: egea j. ACS Chem Neurosci. 2020 Nov 18;11(22):3793-3801. doi: 10.1021/acschemneuro.0c00489. Epub 2020 Nov 3. ACS Chem Neurosci. 2020. PMID: 33143412 Free PMC article.
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.
González-Muñoz GC, Arce MP, López B, Pérez C, Romero A, del Barrio L, Martín-de-Saavedra MD, Egea J, León R, Villarroya M, López MG, García AG, Conde S, Rodríguez-Franco MI. González-Muñoz GC, et al. Among authors: egea j. Eur J Med Chem. 2011 Jun;46(6):2224-35. doi: 10.1016/j.ejmech.2011.03.003. Epub 2011 Mar 21. Eur J Med Chem. 2011. PMID: 21420206
Synthesis and biological assessment of diversely substituted furo[2,3-b]quinolin-4-amine and pyrrolo[2,3-b]quinolin-4-amine derivatives, as novel tacrine analogues.
Martins C, Carreiras MC, León R, de los Ríos C, Bartolini M, Andrisano V, Iriepa I, Moraleda I, Gálvez E, García M, Egea J, Samadi A, Chioua M, Marco-Contelles J. Martins C, et al. Among authors: egea j. Eur J Med Chem. 2011 Dec;46(12):6119-30. doi: 10.1016/j.ejmech.2011.09.038. Epub 2011 Sep 29. Eur J Med Chem. 2011. PMID: 22000936
Novel multitarget ligand ITH33/IQM9.21 provides neuroprotection in in vitro and in vivo models related to brain ischemia.
Lorrio S, Gómez-Rangel V, Negredo P, Egea J, Leon R, Romero A, Dal-Cim T, Villarroya M, Rodriguez-Franco MI, Conde S, Arce MP, Roda JM, García AG, López MG. Lorrio S, et al. Among authors: egea j. Neuropharmacology. 2013 Apr;67:403-11. doi: 10.1016/j.neuropharm.2012.12.001. Epub 2012 Dec 7. Neuropharmacology. 2013. PMID: 23228428
278 results