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Phosphorylation of FAM134C by CK2 controls starvation-induced ER-phagy.
Di Lorenzo G, Iavarone F, Maddaluno M, Plata-Gómez AB, Aureli S, Quezada Meza CP, Cinque L, Palma A, Reggio A, Cirillo C, Sacco F, Stolz A, Napolitano G, Marin O, Pinna LA, Ruzzene M, Limongelli V, Efeyan A, Grumati P, Settembre C. Di Lorenzo G, et al. Among authors: efeyan a. Sci Adv. 2022 Sep 2;8(35):eabo1215. doi: 10.1126/sciadv.abo1215. Epub 2022 Aug 31. Sci Adv. 2022. PMID: 36044577 Free PMC article.
Limited survival and impaired hepatic fasting metabolism in mice with constitutive Rag GTPase signaling.
de la Calle Arregui C, Plata-Gómez AB, Deleyto-Seldas N, García F, Ortega-Molina A, Abril-Garrido J, Rodriguez E, Nemazanyy I, Tribouillard L, de Martino A, Caleiras E, Campos-Olivas R, Mulero F, Laplante M, Muñoz J, Pende M, Sabio G, Sabatini DM, Efeyan A. de la Calle Arregui C, et al. Among authors: efeyan a. Nat Commun. 2021 Jun 16;12(1):3660. doi: 10.1038/s41467-021-23857-8. Nat Commun. 2021. PMID: 34135321 Free PMC article.
Protocol for the assessment of mTOR activity in mouse primary hepatocytes.
Plata-Gómez AB, Crespo M, de la Calle Arregui C, de Prado-Rivas L, Sabio G, Efeyan A. Plata-Gómez AB, et al. Among authors: efeyan a. STAR Protoc. 2021 Oct 29;2(4):100918. doi: 10.1016/j.xpro.2021.100918. eCollection 2021 Dec 17. STAR Protoc. 2021. PMID: 34755120 Free PMC article.
Hepatic nutrient and hormone signaling to mTORC1 instructs the postnatal metabolic zonation of the liver.
Plata-Gómez AB, de Prado-Rivas L, Sanz A, Deleyto-Seldas N, García F, de la Calle Arregui C, Silva C, Caleiras E, Graña-Castro O, Piñeiro-Yáñez E, Krebs J, Leiva-Vega L, Muñoz J, Jain A, Sabio G, Efeyan A. Plata-Gómez AB, et al. Among authors: efeyan a. Nat Commun. 2024 Mar 18;15(1):1878. doi: 10.1038/s41467-024-46032-1. Nat Commun. 2024. PMID: 38499523 Free PMC article.
Lack of p38 activation in T cells increases IL-35 and protects against obesity by promoting thermogenesis.
Nikolic I, Ruiz-Garrido I, Crespo M, Romero-Becerra R, Leiva-Vega L, Mora A, León M, Rodríguez E, Leiva M, Plata-Gómez AB, Alvarez Flores MB, Torres JL, Hernández-Cosido L, López JA, Vázquez J, Efeyan A, Martin P, Marcos M, Sabio G. Nikolic I, et al. Among authors: efeyan a. EMBO Rep. 2024 May 10. doi: 10.1038/s44319-024-00149-y. Online ahead of print. EMBO Rep. 2024. PMID: 38730210 Free article.
The mTOR-Autophagy Axis and the Control of Metabolism.
Deleyto-Seldas N, Efeyan A. Deleyto-Seldas N, et al. Among authors: efeyan a. Front Cell Dev Biol. 2021 Jul 1;9:655731. doi: 10.3389/fcell.2021.655731. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34277603 Free PMC article. Review.
mTOR and cancer: many loops in one pathway.
Efeyan A, Sabatini DM. Efeyan A, et al. Curr Opin Cell Biol. 2010 Apr;22(2):169-76. doi: 10.1016/j.ceb.2009.10.007. Epub 2009 Nov 27. Curr Opin Cell Biol. 2010. PMID: 19945836 Free PMC article.
54 results