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Shallow whole genome sequencing approach to detect Homologous Recombination Deficiency in the PAOLA-1/ENGOT-OV25 phase-III trial.
Oncogene. 2023 Nov;42(48):3556-3563. doi: 10.1038/s41388-023-02839-8. Epub 2023 Nov 9.
Oncogene. 2023.
PMID: 37945748
Free PMC article.
Clinical Trial.
Homologous recombination deficiency derived from whole-genome sequencing predicts platinum response in triple-negative breast cancers.
Ter Brugge P, Moser SC, Bièche I, Kristel P, Ibadioune S, Eeckhoutte A, de Bruijn R, van der Burg E, Lutz C, Annunziato S, de Ruiter J, Masliah Planchon J, Vacher S, Courtois L, El-Botty R, Dahmani A, Montaudon E, Morisset L, Sourd L, Huguet L, Derrien H, Nemati F, Chateau-Joubert S, Larcher T, Salomon A, Decaudin D, Reyal F, Coussy F, Popova T, Wesseling J, Stern MH, Jonkers J, Marangoni E.
Ter Brugge P, et al. Among authors: eeckhoutte a.
Nat Commun. 2023 Apr 7;14(1):1958. doi: 10.1038/s41467-023-37537-2.
Nat Commun. 2023.
PMID: 37029129
Free PMC article.
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Concurrent Olaparib and Radiotherapy in Patients With Triple-Negative Breast Cancer: The Phase 1 Olaparib and Radiation Therapy for Triple-Negative Breast Cancer Trial.
Loap P, Loirat D, Berger F, Rodrigues M, Bazire L, Pierga JY, Vincent-Salomon A, Laki F, Boudali L, Raizonville L, Mosseri V, Jochem A, Eeckhoutte A, Diallo M, Stern MH, Fourquet A, Kirova Y.
Loap P, et al. Among authors: eeckhoutte a.
JAMA Oncol. 2022 Dec 1;8(12):1802-1808. doi: 10.1001/jamaoncol.2022.5074.
JAMA Oncol. 2022.
PMID: 36301572
Free PMC article.
Clinical Trial.
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Oral Etoposide and Trastuzumab Use for HER2-Positive Metastatic Breast Cancer: A Retrospective Study from the Institut Curie Hospitals.
Chalumeau C, Carton M, Eeckhoutte A, Ballet S, Vincent-Salomon A, Vuagnat P, Bellesoeur A, Pierga JY, Stern MH, Bidard FC, Lerebours F.
Chalumeau C, et al. Among authors: eeckhoutte a.
Cancers (Basel). 2022 Apr 24;14(9):2114. doi: 10.3390/cancers14092114.
Cancers (Basel). 2022.
PMID: 35565244
Free PMC article.
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Genomic Instability Is Defined by Specific Tumor Microenvironment in Ovarian Cancer: A Subgroup Analysis of AGO OVAR 12 Trial.
Fumet JD, Lardenois E, Ray-Coquard I, Harter P, Joly F, Canzler U, Truntzer C, Tredan O, Liebrich C, Lortholary A, Pissaloux D, Leary A, Pfisterer J, Eeckhoutte A, Hilpert F, Fabbro M, Caux C, Alexandre J, Houlier A, Sehouli J, Sohier E, Kimmig R, Dubois B, Spaeth D, Treilleux I, Frenel JS, Herwig U, Le Saux O, Bendriss-Vermare N, du Bois A.
Fumet JD, et al. Among authors: eeckhoutte a.
Cancers (Basel). 2022 Feb 25;14(5):1189. doi: 10.3390/cancers14051189.
Cancers (Basel). 2022.
PMID: 35267497
Free PMC article.
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ShallowHRD: detection of homologous recombination deficiency from shallow whole genome sequencing.
Eeckhoutte A, Houy A, Manié E, Reverdy M, Bièche I, Marangoni E, Goundiam O, Vincent-Salomon A, Stoppa-Lyonnet D, Bidard FC, Stern MH, Popova T.
Eeckhoutte A, et al.
Bioinformatics. 2020 Jun 1;36(12):3888-3889. doi: 10.1093/bioinformatics/btaa261.
Bioinformatics. 2020.
PMID: 32315385
Free PMC article.
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Germline MBD4 Mutations and Predisposition to Uveal Melanoma.
Derrien AC, Rodrigues M, Eeckhoutte A, Dayot S, Houy A, Mobuchon L, Gardrat S, Lequin D, Ballet S, Pierron G, Alsafadi S, Mariani O, El-Marjou A, Matet A, Colas C, Cassoux N, Stern MH.
Derrien AC, et al. Among authors: eeckhoutte a.
J Natl Cancer Inst. 2021 Jan 4;113(1):80-87. doi: 10.1093/jnci/djaa047.
J Natl Cancer Inst. 2021.
PMID: 32239153
Free PMC article.
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Lack of evidence for CDK12 as an ovarian cancer predisposing gene.
Eeckhoutte A, Saint-Ghislain M, Reverdy M, Raynal V, Baulande S, Bataillon G, Golmard L, Stoppa-Lyonnet D, Popova T, Houdayer C, Manié E, Stern MH.
Eeckhoutte A, et al.
Fam Cancer. 2020 Jul;19(3):203-209. doi: 10.1007/s10689-020-00169-2.
Fam Cancer. 2020.
PMID: 32172432
Free article.
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