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Development of ISB 1442, a CD38 and CD47 bispecific biparatopic antibody innate cell modulator for the treatment of multiple myeloma.
Grandclément C, Estoppey C, Dheilly E, Panagopoulou M, Monney T, Dreyfus C, Loyau J, Labanca V, Drake A, De Angelis S, Rubod A, Frei J, Caro LN, Blein S, Martini E, Chimen M, Matthes T, Kaya Z, Edwards CM, Edwards JR, Menoret E, Kervoelen C, Pellat-Deceunynck C, Moreau P, Mbow ML, Srivastava A, Dyson MR, Zhukovsky EA, Perro M, Sammicheli S. Grandclément C, et al. Among authors: edwards jr. Nat Commun. 2024 Mar 6;15(1):2054. doi: 10.1038/s41467-024-46310-y. Nat Commun. 2024. PMID: 38448430 Free PMC article.
A human mitofusin 2 mutation can cause mitophagic cardiomyopathy.
Franco A, Li J, Kelly DP, Hershberger RE, Marian AJ, Lewis RM, Song M, Dang X, Schmidt AD, Mathyer ME, Edwards JR, Strong CG, Dorn GW. Franco A, et al. Among authors: edwards jr. Elife. 2023 Nov 1;12:e84235. doi: 10.7554/eLife.84235. Elife. 2023. PMID: 37910431 Free PMC article.
Preclinical characterization of ISB 1342, a CD38 × CD3 T-cell engager for relapsed/refractory multiple myeloma.
Pouleau B, Estoppey C, Suere P, Nallet E, Laurendon A, Monney T, Pais Ferreira D, Drake A, Carretero-Iglesia L, Macoin J, Berret J, Pihlgren M, Doucey MA, Gudi GS, Menon V, Udupa V, Maiti A, Borthakur G, Srivastava A, Blein S, Mbow ML, Matthes T, Kaya Z, Edwards CM, Edwards JR, Menoret E, Kervoëlen C, Pellat-Deceunynck C, Moreau P, Zhukovsky E, Perro M, Chimen M. Pouleau B, et al. Among authors: edwards jr. Blood. 2023 Jul 20;142(3):260-273. doi: 10.1182/blood.2022019451. Blood. 2023. PMID: 37192303 Free PMC article.
889 results