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Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes.
J Med Chem. 2021 Aug 12;64(15):10849-10877. doi: 10.1021/acs.jmedchem.0c02274. Epub 2021 Jul 15.
J Med Chem. 2021.
PMID: 34264658
Free PMC article.
In Depth Analysis of Kinase Cross Screening Data to Identify CAMKK2 Inhibitory Scaffolds.
O'Byrne SN, Scott JW, Pilotte JR, Santiago ADS, Langendorf CG, Oakhill JS, Eduful BJ, Couñago RM, Wells CI, Zuercher WJ, Willson TM, Drewry DH.
O'Byrne SN, et al. Among authors: eduful bj.
Molecules. 2020 Jan 13;25(2):325. doi: 10.3390/molecules25020325.
Molecules. 2020.
PMID: 31941153
Free PMC article.
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Concise, gram-scale synthesis of furo[2,3-b]pyridines with functional handles for chemoselective cross-coupling.
O'Byrne SN, Eduful BJ, Willson TM, Drewry DH.
O'Byrne SN, et al. Among authors: eduful bj.
Tetrahedron Lett. 2020 Sep 17;61(38):152353. doi: 10.1016/j.tetlet.2020.152353. Epub 2020 Aug 16.
Tetrahedron Lett. 2020.
PMID: 33012852
Free PMC article.
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Non-canonical role of Hippo tumor suppressor serine/threonine kinase 3 STK3 in prostate cancer.
Schirmer AU, Driver LM, Zhao MT, Wells CI, Pickett JE, O'Bryne SN, Eduful BJ, Yang X, Howard L, You S, Devi GR, DiGiovanni J, Freedland SJ, Chi JT, Drewry DH, Macias E.
Schirmer AU, et al. Among authors: eduful bj.
Mol Ther. 2022 Jan 5;30(1):485-500. doi: 10.1016/j.ymthe.2021.08.029. Epub 2021 Aug 25.
Mol Ther. 2022.
PMID: 34450249
Free PMC article.
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Synthesis and Activity of a New Series of Antileishmanial Agents.
Kanwar A, Eduful BJ, Barbeto L, Carletti Bonomo P, Lemus A, Vesely BA, Mutka TS, Azhari A, Kyle DE, Leahy JW.
Kanwar A, et al. Among authors: eduful bj.
ACS Med Chem Lett. 2017 Jul 31;8(8):797-801. doi: 10.1021/acsmedchemlett.7b00039. eCollection 2017 Aug 10.
ACS Med Chem Lett. 2017.
PMID: 28835791
Free PMC article.
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