Edgington-Mitchell LE - Search Results

1

N-Terminomics/TAILS Profiling of Proteases and Their Substrates in Ulcerative Colitis.

Gordon MH, Anowai A, Young D, Das N, Campden RI, Sekhon H, Myers Z, Mainoli B, Chopra S, Thuy-Boun PS, Kizhakkedathu J, Bindra G, Jijon HB, Heitman S, Yates R, Wolan DW, Edgington-Mitchell LE, MacNaughton WK, Dufour A. Gordon MH, et al. ACS Chem Biol. 2019 Nov 15;14(11):2471-2483. doi: 10.1021/acschembio.9b00608. Epub 2019 Aug 21. ACS Chem Biol. 2019. PMID: 31393699

2

N-Terminomics/TAILS Profiling of Macrophages after Chemical Inhibition of Legumain.

Anderson BM, de Almeida LGN, Sekhon H, Young D, Dufour A, Edgington-Mitchell LE. Anderson BM, et al. Biochemistry. 2020 Jan 28;59(3):329-340. doi: 10.1021/acs.biochem.9b00821. Epub 2019 Nov 27. Biochemistry. 2020. PMID: 31774660

3

Proteomics and Imaging in Crohn's Disease: TAILS of Unlikely Allies.

Mainoli B, Hirota S, Edgington-Mitchell LE, Lu C, Dufour A. Mainoli B, et al. Trends Pharmacol Sci. 2020 Feb;41(2):74-84. doi: 10.1016/j.tips.2019.11.008. Epub 2020 Jan 14. Trends Pharmacol Sci. 2020. PMID: 31952817 Review.

4

Application of a Sulfoxonium Ylide Electrophile to Generate Cathepsin X-Selective Activity-Based Probes.

Mountford SJ, Anderson BM, Xu B, Tay ESV, Szabo M, Hoang ML, Diao J, Aurelio L, Campden RI, Lindström E, Sloan EK, Yates RM, Bunnett NW, Thompson PE, Edgington-Mitchell LE. Mountford SJ, et al. ACS Chem Biol. 2020 Mar 20;15(3):718-727. doi: 10.1021/acschembio.9b00961. Epub 2020 Feb 14. ACS Chem Biol. 2020. PMID: 32022538 Free PMC article.

5

Pathophysiological roles of proteases in gastrointestinal disease.

Edgington-Mitchell LE. Edgington-Mitchell LE. Am J Physiol Gastrointest Liver Physiol. 2016 Feb 15;310(4):G234-9. doi: 10.1152/ajpgi.00393.2015. Epub 2015 Dec 23. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 26702140 Free article. Review.

6

Application of a chemical probe to detect neutrophil elastase activation during inflammatory bowel disease.

Anderson BM, Poole DP, Aurelio L, Ng GZ, Fleischmann M, Kasperkiewicz P, Morissette C, Drag M, van Driel IR, Schmidt BL, Vanner SJ, Bunnett NW, Edgington-Mitchell LE. Anderson BM, et al. Sci Rep. 2019 Sep 16;9(1):13295. doi: 10.1038/s41598-019-49840-4. Sci Rep. 2019. PMID: 31527638 Free PMC article.

7

Chemical Tools to Image the Activity of PAR-Cleaving Proteases.

Lee IY, Tantisirivat P, Edgington-Mitchell LE. Lee IY, et al. Among authors: edgington mitchell le. ACS Bio Med Chem Au. 2023 May 27;3(4):295-304. doi: 10.1021/acsbiomedchemau.3c00019. eCollection 2023 Aug 16. ACS Bio Med Chem Au. 2023. PMID: 37599791 Free PMC article. Review.

8

Demonstration of elevated levels of active cathepsin S in dextran sulfate sodium colitis using a new activatable probe.

Barlow N, Nasser Y, Zhao P, Sharma N, Guerrero-Alba R, Edgington-Mitchell LE, Lieu T, Veldhuis NA, Poole DP, Conner JW, Lindström E, Craig AW, Graham B, Vanner SJ, Bunnett NW. Barlow N, et al. Neurogastroenterol Motil. 2015 Nov;27(11):1675-80. doi: 10.1111/nmo.12656. Epub 2015 Aug 24. Neurogastroenterol Motil. 2015. PMID: 26303377

9

Editorial overview: Systems biology and the rise and rise of omics approaches.

Scott NE, Edgington-Mitchell LE. Scott NE, et al. Curr Opin Chem Biol. 2021 Jan 5:S1367-5931(20)30160-5. doi: 10.1016/j.cbpa.2020.12.001. Online ahead of print. Curr Opin Chem Biol. 2021. PMID: 33419639 No abstract available.

10

Editorial overview: Systems biology and the rise and rise of omics approaches.

Scott NE, Edgington-Mitchell LE. Scott NE, et al. Curr Opin Chem Biol. 2021 Feb;60:A1-A3. doi: 10.1016/j.cbpa.2021.02.006. Curr Opin Chem Biol. 2021. PMID: 33676636 No abstract available.

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