Edgell DR - Search Results

1

Applications of Alternative Nucleases in the Age of CRISPR/Cas9.

Guha TK, Edgell DR. Guha TK, et al. Among authors: edgell dr. Int J Mol Sci. 2017 Nov 29;18(12):2565. doi: 10.3390/ijms18122565. Int J Mol Sci. 2017. PMID: 29186020 Free PMC article. Review.

2

Monomeric site-specific nucleases for genome editing.

Kleinstiver BP, Wolfs JM, Kolaczyk T, Roberts AK, Hu SX, Edgell DR. Kleinstiver BP, et al. Among authors: edgell dr. Proc Natl Acad Sci U S A. 2012 May 22;109(21):8061-6. doi: 10.1073/pnas.1117984109. Epub 2012 May 7. Proc Natl Acad Sci U S A. 2012. PMID: 22566637 Free PMC article.

3

Biasing genome-editing events toward precise length deletions with an RNA-guided TevCas9 dual nuclease.

Wolfs JM, Hamilton TA, Lant JT, Laforet M, Zhang J, Salemi LM, Gloor GB, Schild-Poulter C, Edgell DR. Wolfs JM, et al. Among authors: edgell dr. Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):14988-14993. doi: 10.1073/pnas.1616343114. Epub 2016 Dec 12. Proc Natl Acad Sci U S A. 2016. PMID: 27956611 Free PMC article.

4

An Expanded Plasmid-Based Genetic Toolbox Enables Cas9 Genome Editing and Stable Maintenance of Synthetic Pathways in Phaeodactylum tricornutum.

Slattery SS, Diamond A, Wang H, Therrien JA, Lant JT, Jazey T, Lee K, Klassen Z, Desgagné-Penix I, Karas BJ, Edgell DR. Slattery SS, et al. Among authors: edgell dr. ACS Synth Biol. 2018 Feb 16;7(2):328-338. doi: 10.1021/acssynbio.7b00191. Epub 2018 Jan 8. ACS Synth Biol. 2018. PMID: 29298053

5

mitoTev-TALE: a monomeric DNA editing enzyme to reduce mutant mitochondrial DNA levels.

Pereira CV, Bacman SR, Arguello T, Zekonyte U, Williams SL, Edgell DR, Moraes CT. Pereira CV, et al. Among authors: edgell dr. EMBO Mol Med. 2018 Sep;10(9):e8084. doi: 10.15252/emmm.201708084. EMBO Mol Med. 2018. PMID: 30012581 Free PMC article.

6

Trans-Kingdom Conjugation within Solid Media from Escherichia coli to Saccharomyces cerevisiae.

Soltysiak MPM, Meaney RS, Hamadache S, Janakirama P, Edgell DR, Karas BJ. Soltysiak MPM, et al. Among authors: edgell dr. Int J Mol Sci. 2019 Oct 21;20(20):5212. doi: 10.3390/ijms20205212. Int J Mol Sci. 2019. PMID: 31640164 Free PMC article.

7

Plasmid-based complementation of large deletions in Phaeodactylum tricornutum biosynthetic genes generated by Cas9 editing.

Slattery SS, Wang H, Giguere DJ, Kocsis C, Urquhart BL, Karas BJ, Edgell DR. Slattery SS, et al. Among authors: edgell dr. Sci Rep. 2020 Aug 17;10(1):13879. doi: 10.1038/s41598-020-70769-6. Sci Rep. 2020. PMID: 32807825 Free PMC article.

8

A generalizable Cas9/sgRNA prediction model using machine transfer learning with small high-quality datasets.

Ham DT, Browne TS, Banglorewala PN, Wilson TL, Michael RK, Gloor GB, Edgell DR. Ham DT, et al. Among authors: edgell dr. Nat Commun. 2023 Sep 7;14(1):5514. doi: 10.1038/s41467-023-41143-7. Nat Commun. 2023. PMID: 37679324 Free PMC article.

9

Mobile DNA elements in T4 and related phages.

Edgell DR, Gibb EA, Belfort M. Edgell DR, et al. Virol J. 2010 Oct 28;7:290. doi: 10.1186/1743-422X-7-290. Virol J. 2010. PMID: 21029434 Free PMC article. Review.

10

Rapid screening of endonuclease target site preference using a modified bacterial two-plasmid selection.

Wolfs JM, Kleinstiver BP, Edgell DR. Wolfs JM, et al. Among authors: edgell dr. Methods Mol Biol. 2014;1123:97-104. doi: 10.1007/978-1-62703-968-0_8. Methods Mol Biol. 2014. PMID: 24510263

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