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Blocking IL-6 signaling prevents astrocyte-induced neurodegeneration in an iPSC-based model of Parkinson's disease.
Pons-Espinal M, Blasco-Agell L, Fernandez-Carasa I, Andrés-Benito P, di Domenico A, Richaud-Patin Y, Baruffi V, Marruecos L, Espinosa L, Garrido A, Tolosa E, Edel MJ, Otero MJ, Mosquera JL, Ferrer I, Raya A, Consiglio A. Pons-Espinal M, et al. Among authors: edel mj. JCI Insight. 2024 Feb 8;9(3):e163359. doi: 10.1172/jci.insight.163359. JCI Insight. 2024. PMID: 38329129 Free PMC article.
A Hyaluronic Acid Demilune Scaffold and Polypyrrole-Coated Fibers Carrying Embedded Human Neural Precursor Cells and Curcumin for Surface Capping of Spinal Cord Injuries.
Elkhenany H, Bonilla P, Giraldo E, Alastrue Agudo A, Edel MJ, Vicent MJ, Roca FG, Ramos CM, Doblado LR, Pradas MM, Manzano VM. Elkhenany H, et al. Among authors: edel mj. Biomedicines. 2021 Dec 16;9(12):1928. doi: 10.3390/biomedicines9121928. Biomedicines. 2021. PMID: 34944744 Free PMC article.
A synthetic mRNA cell reprogramming method using CYCLIN D1 promotes DNA repair, generating improved genetically stable human induced pluripotent stem cells.
Alvarez-Palomo AB, Requena-Osete J, Delgado-Morales R, Moreno-Manzano V, Grau-Bove C, Tejera AM, Otero MJ, Barrot C, Santos-Barriopedro I, Vaquero A, Mezquita-Pla J, Moran S, Naya CH, Garcia-Martínez I, Pérez FV, Blasco MA, Esteller M, Edel MJ. Alvarez-Palomo AB, et al. Among authors: edel mj. Stem Cells. 2021 Jul;39(7):866-881. doi: 10.1002/stem.3358. Epub 2021 Mar 3. Stem Cells. 2021. PMID: 33621399
Two novel ligand-independent variants of the VEGFR-1 receptor are expressed in human testis and spermatozoa, one of them with the ability to activate SRC proto-oncogene tyrosine kinases.
Alvarez-Palomo B, Barrot-Feixat C, Sarret H, Requena J, Pau M, Vidal-Taboada JM, Oliva R, Ballesca JL, Edel MJ, Mezquita-Pla J. Alvarez-Palomo B, et al. Among authors: edel mj. Oncotarget. 2019 Oct 8;10(56):5871-5887. doi: 10.18632/oncotarget.27232. eCollection 2019 Oct 8. Oncotarget. 2019. PMID: 31645906 Free PMC article.
Global Proteomic and Methylome Analysis in Human Induced Pluripotent Stem Cells Reveals Overexpression of a Human TLR3 Affecting Proper Innate Immune Response Signaling.
Requena J, Alvarez-Palomo AB, Codina-Pascual M, Delgado-Morales R, Moran S, Esteller M, Sal M, Juan M, Boronat Barado A, Consiglio A, Bogle OA, Wolvetang E, Ovchinnikov D, Alvarez I, Jaraquemada D, Mezquita-Pla J, Oliva R, Edel MJ. Requena J, et al. Among authors: edel mj. Stem Cells. 2019 Apr;37(4):476-488. doi: 10.1002/stem.2966. Epub 2019 Feb 14. Stem Cells. 2019. PMID: 30664289 Free PMC article.
35 results