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Caspase-4/11 exacerbates disease severity in SARS-CoV-2 infection by promoting inflammation and immunothrombosis.
Eltobgy MM, Zani A, Kenney AD, Estfanous S, Kim E, Badr A, Carafice C, Daily K, Whitham O, Pietrzak M, Webb A, Kawahara J, Eddy AC, Denz P, Lu M, Kc M, Peeples ME, Li J, Zhu J, Que J, Robinson R, Rosas Mejia O, Rayner RE, Hall-Stoodley L, Seveau S, Gavrilin MA, Zhang X, Thomas J, Kohlmeier JE, Suthar MS, Oltz E, Tedeschi A, Robledo-Avila FH, Partida-Sanchez S, Hemann EA, Abdelrazik E, Forero A, Nimjee SM, Boyaka PN, Cormet-Boyaka E, Yount JS, Amer AO. Eltobgy MM, et al. Among authors: eddy ac. Proc Natl Acad Sci U S A. 2022 May 24;119(21):e2202012119. doi: 10.1073/pnas.2202012119. Epub 2022 May 19. Proc Natl Acad Sci U S A. 2022. PMID: 35588457 Free PMC article.
Influenza virus replication in cardiomyocytes drives heart dysfunction and fibrosis.
Kenney AD, Aron SL, Gilbert C, Kumar N, Chen P, Eddy A, Zhang L, Zani A, Vargas-Maldonado N, Speaks S, Kawahara J, Denz PJ, Dorn L, Accornero F, Ma J, Zhu H, Rajaram MVS, Cai C, Langlois RA, Yount JS. Kenney AD, et al. Sci Adv. 2022 May 13;8(19):eabm5371. doi: 10.1126/sciadv.abm5371. Epub 2022 May 11. Sci Adv. 2022. PMID: 35544568 Free PMC article.
Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2.
Shi G, Chiramel AI, Li T, Lai KK, Kenney AD, Zani A, Eddy AC, Majdoul S, Zhang L, Dempsey T, Beare PA, Kar S, Yewdell JW, Best SM, Yount JS, Compton AA. Shi G, et al. Among authors: eddy ac. J Clin Invest. 2022 Dec 15;132(24):e160766. doi: 10.1172/JCI160766. J Clin Invest. 2022. PMID: 36264642 Free PMC article.
Pro-angiogenic therapeutics for preeclampsia.
Eddy AC, Bidwell GL 3rd, George EM. Eddy AC, et al. Biol Sex Differ. 2018 Aug 25;9(1):36. doi: 10.1186/s13293-018-0195-5. Biol Sex Differ. 2018. PMID: 30144822 Free PMC article. Review.
47 results