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Page 1
Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragment.
Danis C, Dupré E, Zejneli O, Caillierez R, Arrial A, Bégard S, Mortelecque J, Eddarkaoui S, Loyens A, Cantrelle FX, Hanoulle X, Rain JC, Colin M, Buée L, Landrieu I. Danis C, et al. Among authors: eddarkaoui s. Mol Ther. 2022 Apr 6;30(4):1484-1499. doi: 10.1016/j.ymthe.2022.01.009. Epub 2022 Jan 7. Mol Ther. 2022. PMID: 35007758 Free PMC article.
Tau accumulation in astrocytes of the dentate gyrus induces neuronal dysfunction and memory deficits in Alzheimer's disease.
Richetin K, Steullet P, Pachoud M, Perbet R, Parietti E, Maheswaran M, Eddarkaoui S, Bégard S, Pythoud C, Rey M, Caillierez R, Q Do K, Halliez S, Bezzi P, Buée L, Leuba G, Colin M, Toni N, Déglon N. Richetin K, et al. Among authors: eddarkaoui s. Nat Neurosci. 2020 Dec;23(12):1567-1579. doi: 10.1038/s41593-020-00728-x. Epub 2020 Nov 9. Nat Neurosci. 2020. PMID: 33169029
Brain insulin response and peripheral metabolic changes in a Tau transgenic mouse model.
Leboucher A, Ahmed T, Caron E, Tailleux A, Raison S, Joly-Amado A, Marciniak E, Carvalho K, Hamdane M, Bantubungi K, Lancel S, Eddarkaoui S, Caillierez R, Vallez E, Staels B, Vieau D, Balschun D, Buee L, Blum D. Leboucher A, et al. Among authors: eddarkaoui s. Neurobiol Dis. 2019 May;125:14-22. doi: 10.1016/j.nbd.2019.01.008. Epub 2019 Jan 19. Neurobiol Dis. 2019. PMID: 30665005
Exacerbation of C1q dysregulation, synaptic loss and memory deficits in tau pathology linked to neuronal adenosine A2A receptor.
Carvalho K, Faivre E, Pietrowski MJ, Marques X, Gomez-Murcia V, Deleau A, Huin V, Hansen JN, Kozlov S, Danis C, Temido-Ferreira M, Coelho JE, Mériaux C, Eddarkaoui S, Gras SL, Dumoulin M, Cellai L; NeuroCEB Brain Bank; Landrieu I, Chern Y, Hamdane M, Buée L, Boutillier AL, Levi S, Halle A, Lopes LV, Blum D. Carvalho K, et al. Among authors: eddarkaoui s. Brain. 2019 Nov 1;142(11):3636-3654. doi: 10.1093/brain/awz288. Brain. 2019. PMID: 31599329 Free PMC article.
Tau pathology modulates Pin1 post-translational modifications and may be relevant as biomarker.
Ando K, Dourlen P, Sambo AV, Bretteville A, Bélarbi K, Vingtdeux V, Eddarkaoui S, Drobecq H, Ghestem A, Bégard S, Demey-Thomas E, Melnyk P, Smet C, Lippens G, Maurage CA, Caillet-Boudin ML, Verdier Y, Vinh J, Landrieu I, Galas MC, Blum D, Hamdane M, Sergeant N, Buée L. Ando K, et al. Among authors: eddarkaoui s. Neurobiol Aging. 2013 Mar;34(3):757-69. doi: 10.1016/j.neurobiolaging.2012.08.004. Epub 2012 Aug 25. Neurobiol Aging. 2013. PMID: 22926167
P2X7-deficiency improves plasticity and cognitive abilities in a mouse model of Tauopathy.
Carvalho K, Martin E, Ces A, Sarrazin N, Lagouge-Roussey P, Nous C, Boucherit L, Youssef I, Prigent A, Faivre E, Eddarkaoui S, Gauvrit T, Vieau D, Boluda S, Huin V, Fontaine B, Buée L, Delatour B, Dutar P, Sennlaub F, Guillonneau X, Blum D, Delarasse C; NeuroCEB Brain Bank. Carvalho K, et al. Among authors: eddarkaoui s. Prog Neurobiol. 2021 Nov;206:102139. doi: 10.1016/j.pneurobio.2021.102139. Epub 2021 Aug 12. Prog Neurobiol. 2021. PMID: 34391810 Free article.
Detrimental effects of diet-induced obesity on τ pathology are independent of insulin resistance in τ transgenic mice.
Leboucher A, Laurent C, Fernandez-Gomez FJ, Burnouf S, Troquier L, Eddarkaoui S, Demeyer D, Caillierez R, Zommer N, Vallez E, Bantubungi K, Breton C, Pigny P, Buée-Scherrer V, Staels B, Hamdane M, Tailleux A, Buée L, Blum D. Leboucher A, et al. Among authors: eddarkaoui s. Diabetes. 2013 May;62(5):1681-8. doi: 10.2337/db12-0866. Epub 2012 Dec 18. Diabetes. 2013. PMID: 23250356 Free PMC article.
35 results