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Linsitinib, an IGF-1R inhibitor, attenuates disease development and progression in a model of thyroid eye disease.
Gulbins A, Horstmann M, Daser A, Flögel U, Oeverhaus M, Bechrakis NE, Banga JP, Keitsch S, Wilker B, Krause G, Hammer GD, Spencer AG, Zeidan R, Eckstein A, Philipp S, Görtz GE. Gulbins A, et al. Among authors: eckstein a. Front Endocrinol (Lausanne). 2023 Jun 26;14:1211473. doi: 10.3389/fendo.2023.1211473. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37435490 Free PMC article.
Autoantibodies to the IGF1 receptor in Graves' orbitopathy.
Minich WB, Dehina N, Welsink T, Schwiebert C, Morgenthaler NG, Köhrle J, Eckstein A, Schomburg L. Minich WB, et al. Among authors: eckstein a. J Clin Endocrinol Metab. 2013 Feb;98(2):752-60. doi: 10.1210/jc.2012-1771. Epub 2012 Dec 21. J Clin Endocrinol Metab. 2013. PMID: 23264397
Modeling Graves' Orbitopathy in Experimental Graves' Disease.
Banga JP, Moshkelgosha S, Berchner-Pfannschmidt U, Eckstein A. Banga JP, et al. Among authors: eckstein a. Horm Metab Res. 2015 Sep;47(10):797-803. doi: 10.1055/s-0035-1555956. Epub 2015 Aug 19. Horm Metab Res. 2015. PMID: 26287396 Review.
Comparative Assessment of Female Mouse Model of Graves' Orbitopathy Under Different Environments, Accompanied by Proinflammatory Cytokine and T-Cell Responses to Thyrotropin Hormone Receptor Antigen.
Berchner-Pfannschmidt U, Moshkelgosha S, Diaz-Cano S, Edelmann B, Görtz GE, Horstmann M, Noble A, Hansen W, Eckstein A, Banga JP. Berchner-Pfannschmidt U, et al. Among authors: eckstein a. Endocrinology. 2016 Apr;157(4):1673-82. doi: 10.1210/en.2015-1829. Epub 2016 Feb 12. Endocrinology. 2016. PMID: 26872090
224 results