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Senescent cells exacerbate chronic inflammation and contribute to periodontal disease progression in old mice.
J Periodontol. 2021 Oct;92(10):1483-1495. doi: 10.1002/JPER.20-0529. Epub 2021 Jan 6.
J Periodontol. 2021.
PMID: 33341947
Free PMC article.
Independent Roles of Estrogen Deficiency and Cellular Senescence in the Pathogenesis of Osteoporosis: Evidence in Young Adult Mice and Older Humans.
Farr JN, Rowsey JL, Eckhardt BA, Thicke BS, Fraser DG, Tchkonia T, Kirkland JL, Monroe DG, Khosla S.
Farr JN, et al. Among authors: eckhardt ba.
J Bone Miner Res. 2019 Aug;34(8):1407-1418. doi: 10.1002/jbmr.3729. Epub 2019 Jun 21.
J Bone Miner Res. 2019.
PMID: 30913313
Free PMC article.
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LPS-induced premature osteocyte senescence: Implications in inflammatory alveolar bone loss and periodontal disease pathogenesis.
Aquino-Martinez R, Rowsey JL, Fraser DG, Eckhardt BA, Khosla S, Farr JN, Monroe DG.
Aquino-Martinez R, et al. Among authors: eckhardt ba.
Bone. 2020 Mar;132:115220. doi: 10.1016/j.bone.2019.115220. Epub 2020 Jan 2.
Bone. 2020.
PMID: 31904537
Free PMC article.
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Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism.
Weivoda MM, Chew CK, Monroe DG, Farr JN, Atkinson EJ, Geske JR, Eckhardt B, Thicke B, Ruan M, Tweed AJ, McCready LK, Rizza RA, Matveyenko A, Kassem M, Andersen TL, Vella A, Drake MT, Clarke BL, Oursler MJ, Khosla S.
Weivoda MM, et al.
Nat Commun. 2020 Jan 7;11(1):87. doi: 10.1038/s41467-019-14003-6.
Nat Commun. 2020.
PMID: 31911667
Free PMC article.
Clinical Trial.
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Accelerated osteocyte senescence and skeletal fragility in mice with type 2 diabetes.
Eckhardt BA, Rowsey JL, Thicke BS, Fraser DG, O'Grady KL, Bondar OP, Hines JM, Singh RJ, Thoreson AR, Rakshit K, Lagnado AB, Passos JF, Vella A, Matveyenko AV, Khosla S, Monroe DG, Farr JN.
Eckhardt BA, et al.
JCI Insight. 2020 May 7;5(9):e135236. doi: 10.1172/jci.insight.135236.
JCI Insight. 2020.
PMID: 32267250
Free PMC article.
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Development and Application of Mass Spectroscopy Assays for Nε-(1-Carboxymethyl)-L-Lysine and Pentosidine in Renal Failure and Diabetes.
O'Grady KL, Khosla S, Farr JN, Bondar OP, Atkinson EJ, Achenbach SJ, Eckhardt BA, Thicke BS, Tweed AJ, Volkman TL, Drake MT, Hines JM, Singh RJ.
O'Grady KL, et al. Among authors: eckhardt ba.
J Appl Lab Med. 2020 May 1;5(3):558-568. doi: 10.1093/jalm/jfaa023.
J Appl Lab Med. 2020.
PMID: 32445362
Free PMC article.
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Skeletal Effects of Inducible ERα Deletion in Osteocytes in Adult Mice.
Doolittle ML, Saul D, Kaur J, Rowsey JL, Eckhardt B, Vos S, Grain S, Kroupova K, Ruan M, Weivoda M, Oursler MJ, Farr JN, Monroe DG, Khosla S.
Doolittle ML, et al.
J Bone Miner Res. 2022 Sep;37(9):1750-1760. doi: 10.1002/jbmr.4644. Epub 2022 Jul 22.
J Bone Miner Res. 2022.
PMID: 35789113
Free PMC article.
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Modest Effects of Osteoclast-Specific ERα Deletion after Skeletal Maturity.
Doolittle ML, Eckhardt BA, Vos SJ, Grain S, Rowsey JL, Ruan M, Saul D, Farr JN, Weivoda MM, Khosla S, Monroe DG.
Doolittle ML, et al. Among authors: eckhardt ba.
JBMR Plus. 2023 Jul 13;7(10):e10797. doi: 10.1002/jbm4.10797. eCollection 2023 Oct.
JBMR Plus. 2023.
PMID: 37808391
Free PMC article.
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