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Mouse models of pediatric high-grade gliomas with MYCN amplification reveal intratumoral heterogeneity and lineage signatures.
Schoof M, Godbole S, Albert TK, Dottermusch M, Walter C, Ballast A, Qin N, Olivera MB, Göbel C, Neyazi S, Holdhof D, Kresbach C, Peter LS, Epplen GD, Thaden V, Spohn M, Blattner-Johnson M, Modemann F, Mynarek M, Rutkowski S, Sill M, Varghese J, Afflerbach AK, Eckhardt A, Münter D, Verma A, Struve N, Jones DTW, Remke M, Neumann JE, Kerl K, Schüller U. Schoof M, et al. Among authors: eckhardt a. Nat Commun. 2023 Nov 24;14(1):7717. doi: 10.1038/s41467-023-43564-w. Nat Commun. 2023. PMID: 38001143 Free PMC article.
Preclinical patient-derived modeling of castration-resistant prostate cancer facilitates individualized assessment of homologous recombination repair deficient disease.
Elsesy ME, Oh-Hohenhorst SJ, Oing C, Eckhardt A, Burdak-Rothkamm S, Alawi M, Müller C, Schüller U, Maurer T, von Amsberg G, Petersen C, Rothkamm K, Mansour WY. Elsesy ME, et al. Among authors: eckhardt a. Mol Oncol. 2023 Jun;17(6):1129-1147. doi: 10.1002/1878-0261.13382. Epub 2023 Mar 16. Mol Oncol. 2023. PMID: 36694344 Free PMC article.
Atypical neurofibromas reveal distinct epigenetic features with proximity to benign peripheral nerve sheath tumor entities.
Kresbach C, Dottermusch M, Eckhardt A, Ristow I, Paplomatas P, Altendorf L, Wefers AK, Bockmayr M, Belakhoua S, Tran I, Pohl L, Neyazi S, Bode H, Farschtschi S, Well L, Friedrich RE, Reuss D, Snuderl M, Hagel C, Mautner VF, Schüller U. Kresbach C, et al. Among authors: eckhardt a. Neuro Oncol. 2023 Sep 5;25(9):1644-1655. doi: 10.1093/neuonc/noad053. Neuro Oncol. 2023. PMID: 36866403 Free PMC article.
Recurrent atypical teratoid/rhabdoid tumors (AT/RT) reveal discrete features of progression on histology, epigenetics, copy number profiling, and transcriptomics.
Johann PD, Altendorf L, Efremova EM, Holsten T, Steinbügl M, Nemes K, Eckhardt A, Kresbach C, Bockmayr M, Koch A, Haberler C, Antonelli M, DeSisto J, Schuhmann MU, Hauser P, Siebert R, Bens S, Kool M, Green AL, Hasselblatt M, Frühwald MC, Schüller U. Johann PD, et al. Among authors: eckhardt a. Acta Neuropathol. 2023 Sep;146(3):527-541. doi: 10.1007/s00401-023-02608-7. Epub 2023 Jul 14. Acta Neuropathol. 2023. PMID: 37450044 Free PMC article.
Epigenetic profiling reveals a strong association between lack of 5-ALA fluorescence and EGFR amplification in IDH-wildtype glioblastoma.
Drexler R, Sauvigny T, Schüller U, Eckhardt A, Maire CL, Khatri R, Hausmann F, Hänzelmann S, Huber TB, Bonn S, Bode H, Lamszus K, Westphal M, Dührsen L, Ricklefs FL. Drexler R, et al. Among authors: eckhardt a. Neurooncol Pract. 2023 May 2;10(5):462-471. doi: 10.1093/nop/npad025. eCollection 2023 Oct. Neurooncol Pract. 2023. PMID: 37720395 Free PMC article.
Molecular refinement of pilocytic astrocytoma in adult patients.
Bode H, Kresbach C, Holdhof D, Dorostkar MM, Harter PN, Hench J, Frank S, Suwala AK, Schweizer L, Eckhardt A, Neyazi S, Bockmayr M, Wefers AK, Schüller U. Bode H, et al. Among authors: eckhardt a. Neuropathol Appl Neurobiol. 2023 Dec 19:e12949. doi: 10.1111/nan.12949. Online ahead of print. Neuropathol Appl Neurobiol. 2023. PMID: 38112165
Temporal change of DNA methylation subclasses between matched newly diagnosed and recurrent glioblastoma.
Drexler R, Khatri R, Schüller U, Eckhardt A, Ryba A, Sauvigny T, Dührsen L, Mohme M, Ricklefs T, Bode H, Hausmann F, Huber TB, Bonn S, Voß H, Neumann JE, Silverbush D, Hovestadt V, Suvà ML, Lamszus K, Gempt J, Westphal M, Heiland DH, Hänzelmann S, Ricklefs FL. Drexler R, et al. Among authors: eckhardt a. Acta Neuropathol. 2024 Jan 20;147(1):21. doi: 10.1007/s00401-023-02677-8. Acta Neuropathol. 2024. PMID: 38244080 Free PMC article.
227 results