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CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system-New mode of action for caffeine.
Ale-Agha N, Goy C, Jakobs P, Spyridopoulos I, Gonnissen S, Dyballa-Rukes N, Aufenvenne K, von Ameln F, Zurek M, Spannbrucker T, Eckermann O, Jakob S, Gorressen S, Abrams M, Grandoch M, Fischer JW, Köhrer K, Deenen R, Unfried K, Altschmied J, Haendeler J. Ale-Agha N, et al. Among authors: eckermann o. PLoS Biol. 2018 Jun 21;16(6):e2004408. doi: 10.1371/journal.pbio.2004408. eCollection 2018 Jun. PLoS Biol. 2018. PMID: 29927970 Free PMC article.
The Anti-Apoptotic Properties of APEX1 in the Endothelium Require the First 20 Amino Acids and Converge on Thioredoxin-1.
Dyballa-Rukes N, Jakobs P, Eckers A, Ale-Agha N, Serbulea V, Aufenvenne K, Zschauer TC, Rabanter LL, Jakob S, von Ameln F, Eckermann O, Leitinger N, Goy C, Altschmied J, Haendeler J. Dyballa-Rukes N, et al. Among authors: eckermann o. Antioxid Redox Signal. 2017 Apr 20;26(12):616-629. doi: 10.1089/ars.2016.6799. Epub 2017 Feb 22. Antioxid Redox Signal. 2017. PMID: 27835927 Free PMC article.
High Concentration of Low-Density Lipoprotein Results in Disturbances in Mitochondrial Transcription and Functionality in Endothelial Cells.
Gonnissen S, Ptok J, Goy C, Jander K, Jakobs P, Eckermann O, Kaisers W, von Ameln F, Timm J, Ale-Agha N, Haendeler J, Schaal H, Altschmied J. Gonnissen S, et al. Among authors: eckermann o. Oxid Med Cell Longev. 2019 Jun 10;2019:7976382. doi: 10.1155/2019/7976382. eCollection 2019. Oxid Med Cell Longev. 2019. PMID: 31281593 Free PMC article.
Endothelial hyaluronan synthase 3 aggravates acute colitis in an experimental model of inflammatory bowel disease.
Hundhausen C, Schneckmann R, Ostendorf Y, Rimpler J, von Glinski A, Kohlmorgen C, Pasch N, Rolauer L, von Ameln F, Eckermann O, Altschmied J, Ale-Agha N, Haendeler J, Flögel U, Fischer JW, Grandoch M. Hundhausen C, et al. Among authors: eckermann o. Matrix Biol. 2021 Aug;102:20-36. doi: 10.1016/j.matbio.2021.08.001. Epub 2021 Aug 28. Matrix Biol. 2021. PMID: 34464693
Mitochondrial Telomerase Reverse Transcriptase Protects From Myocardial Ischemia/Reperfusion Injury by Improving Complex I Composition and Function.
Ale-Agha N, Jakobs P, Goy C, Zurek M, Rosen J, Dyballa-Rukes N, Metzger S, Greulich J, von Ameln F, Eckermann O, Unfried K, Brack F, Grandoch M, Thielmann M, Kamler M, Gedik N, Kleinbongard P, Heinen A, Heusch G, Gödecke A, Altschmied J, Haendeler J. Ale-Agha N, et al. Among authors: eckermann o. Circulation. 2021 Dec 7;144(23):1876-1890. doi: 10.1161/CIRCULATIONAHA.120.051923. Epub 2021 Oct 21. Circulation. 2021. PMID: 34672678 Free article.
CD34+ gene expression profiling of individual children with very severe aplastic anemia indicates a pathogenic role of integrin receptors and the proapoptotic death ligand TRAIL.
Fischer U, Ruckert C, Hubner B, Eckermann O, Binder V, Bakchoul T, Schuster FR, Merk S, Klein HU, Führer M, Dugas M, Borkhardt A. Fischer U, et al. Among authors: eckermann o. Haematologica. 2012 Sep;97(9):1304-11. doi: 10.3324/haematol.2011.056705. Epub 2012 Feb 7. Haematologica. 2012. PMID: 22315490 Free PMC article.
Highly skewed T-cell receptor V-beta chain repertoire in the bone marrow is associated with response to immunosuppressive drug therapy in children with very severe aplastic anemia.
Schuster FR, Hubner B, Führer M, Eckermann O, Gombert M, Dornmair K, Binder V, Reuther S, Krell P, Keller T, Borkhardt A. Schuster FR, et al. Among authors: eckermann o. Blood Cancer J. 2011 Mar;1(3):e8. doi: 10.1038/bcj.2011.6. Epub 2011 Mar 4. Blood Cancer J. 2011. PMID: 22829127 Free PMC article.
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