Ecker GF - Search Results

1

Kinetics for Drug Discovery: an industry-driven effort to target drug residence time.

Schuetz DA, de Witte WEA, Wong YC, Knasmueller B, Richter L, Kokh DB, Sadiq SK, Bosma R, Nederpelt I, Heitman LH, Segala E, Amaral M, Guo D, Andres D, Georgi V, Stoddart LA, Hill S, Cooke RM, De Graaf C, Leurs R, Frech M, Wade RC, de Lange ECM, IJzerman AP, Müller-Fahrnow A, Ecker GF. Schuetz DA, et al. Among authors: ecker gf. Drug Discov Today. 2017 Jun;22(6):896-911. doi: 10.1016/j.drudis.2017.02.002. Epub 2017 Apr 13. Drug Discov Today. 2017. PMID: 28412474 Review.

2

Computational models for prediction of interactions with ABC-transporters.

Ecker GF, Stockner T, Chiba P. Ecker GF, et al. Drug Discov Today. 2008 Apr;13(7-8):311-7. doi: 10.1016/j.drudis.2007.12.012. Epub 2008 Mar 14. Drug Discov Today. 2008. PMID: 18405843 Review.

3

Diazepam-bound GABAA receptor models identify new benzodiazepine binding-site ligands.

Richter L, de Graaf C, Sieghart W, Varagic Z, Mörzinger M, de Esch IJ, Ecker GF, Ernst M. Richter L, et al. Among authors: ecker gf. Nat Chem Biol. 2012 Mar 25;8(5):455-64. doi: 10.1038/nchembio.917. Nat Chem Biol. 2012. PMID: 22446838 Free PMC article.

4

Open PHACTS: semantic interoperability for drug discovery.

Williams AJ, Harland L, Groth P, Pettifer S, Chichester C, Willighagen EL, Evelo CT, Blomberg N, Ecker G, Goble C, Mons B. Williams AJ, et al. Drug Discov Today. 2012 Nov;17(21-22):1188-98. doi: 10.1016/j.drudis.2012.05.016. Epub 2012 Jun 7. Drug Discov Today. 2012. PMID: 22683805 Free article. Review.

5

Molecular analysis of the site for 2-arachidonylglycerol (2-AG) on the β₂ subunit of GABA(A) receptors.

Baur R, Kielar M, Richter L, Ernst M, Ecker GF, Sigel E. Baur R, et al. Among authors: ecker gf. J Neurochem. 2013 Jul;126(1):29-36. doi: 10.1111/jnc.12270. Epub 2013 May 3. J Neurochem. 2013. PMID: 23600744 Free article.

6

Scientific competency questions as the basis for semantically enriched open pharmacological space development.

Azzaoui K, Jacoby E, Senger S, Rodríguez EC, Loza M, Zdrazil B, Pinto M, Williams AJ, de la Torre V, Mestres J, Pastor M, Taboureau O, Rarey M, Chichester C, Pettifer S, Blomberg N, Harland L, Williams-Jones B, Ecker GF. Azzaoui K, et al. Among authors: ecker gf. Drug Discov Today. 2013 Sep;18(17-18):843-52. doi: 10.1016/j.drudis.2013.05.008. Epub 2013 May 20. Drug Discov Today. 2013. PMID: 23702085 Free article. Review.

7

How to solve the problems of docking into a symmetric binding site: the example of the HERG channel.

Schiesaro A, Richter L, Ecker GF. Schiesaro A, et al. Among authors: ecker gf. Sci Pharm. 2013 Jul 31;81(3):677-82. doi: 10.3797/scipharm.1307-01. Print 2013 Jul-Sep. Sci Pharm. 2013. PMID: 24106666 Free PMC article.

8

Exploiting open data: a new era in pharmacoinformatics.

Goldmann D, Montanari F, Richter L, Zdrazil B, Ecker GF. Goldmann D, et al. Among authors: ecker gf. Future Med Chem. 2014 Apr;6(5):503-14. doi: 10.4155/fmc.14.13. Future Med Chem. 2014. PMID: 24649954

9

Transmembrane drug transporter - taxonomy, assays, and their role in drug discovery.

Ecker GF. Ecker GF. Drug Discov Today Technol. 2014 Jun;12:e35-6. doi: 10.1016/j.ddtec.2014.04.002. Drug Discov Today Technol. 2014. PMID: 25027373 No abstract available.

10

Transporter taxonomy - a comparison of different transport protein classification schemes.

Viereck M, Gaulton A, Digles D, Ecker GF. Viereck M, et al. Among authors: ecker gf. Drug Discov Today Technol. 2014 Jun;12:e37-46. doi: 10.1016/j.ddtec.2014.03.004. Drug Discov Today Technol. 2014. PMID: 25027374

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

212 results

Search Page