Echave J - Search Results

1

What evolution tells us about protein physics, and protein physics tells us about evolution.

Bastolla U, Dehouck Y, Echave J. Bastolla U, et al. Among authors: echave j. Curr Opin Struct Biol. 2017 Feb;42:59-66. doi: 10.1016/j.sbi.2016.10.020. Epub 2016 Nov 16. Curr Opin Struct Biol. 2017. PMID: 27865208 Review.

2

The interface of protein structure, protein biophysics, and molecular evolution.

Liberles DA, Teichmann SA, Bahar I, Bastolla U, Bloom J, Bornberg-Bauer E, Colwell LJ, de Koning AP, Dokholyan NV, Echave J, Elofsson A, Gerloff DL, Goldstein RA, Grahnen JA, Holder MT, Lakner C, Lartillot N, Lovell SC, Naylor G, Perica T, Pollock DD, Pupko T, Regan L, Roger A, Rubinstein N, Shakhnovich E, Sjölander K, Sunyaev S, Teufel AI, Thorne JL, Thornton JW, Weinreich DM, Whelan S. Liberles DA, et al. Among authors: echave j. Protein Sci. 2012 Jun;21(6):769-85. doi: 10.1002/pro.2071. Epub 2012 Apr 23. Protein Sci. 2012. PMID: 22528593 Free PMC article. Review.

3

Biophysical Models of Protein Evolution: Understanding the Patterns of Evolutionary Sequence Divergence.

Echave J, Wilke CO. Echave J, et al. Annu Rev Biophys. 2017 May 22;46:85-103. doi: 10.1146/annurev-biophys-070816-033819. Epub 2017 Mar 15. Annu Rev Biophys. 2017. PMID: 28301766 Free PMC article. Review.

4

Causes of evolutionary rate variation among protein sites.

Echave J, Spielman SJ, Wilke CO. Echave J, et al. Nat Rev Genet. 2016 Feb;17(2):109-21. doi: 10.1038/nrg.2015.18. Epub 2016 Jan 19. Nat Rev Genet. 2016. PMID: 26781812 Free PMC article. Review.

5

Local packing density is the main structural determinant of the rate of protein sequence evolution at site level.

Yeh SW, Huang TT, Liu JW, Yu SH, Shih CH, Hwang JK, Echave J. Yeh SW, et al. Among authors: echave j. Biomed Res Int. 2014;2014:572409. doi: 10.1155/2014/572409. Epub 2014 Jul 9. Biomed Res Int. 2014. PMID: 25121105 Free PMC article.

6

Relationship between protein thermodynamic constraints and variation of evolutionary rates among sites.

Echave J, Jackson EL, Wilke CO. Echave J, et al. Phys Biol. 2015 Mar 19;12(2):025002. doi: 10.1088/1478-3975/12/2/025002. Phys Biol. 2015. PMID: 25787027 Free PMC article.

7

Beyond Stability Constraints: A Biophysical Model of Enzyme Evolution with Selection on Stability and Activity.

Echave J. Echave J. Mol Biol Evol. 2019 Mar 1;36(3):613-620. doi: 10.1093/molbev/msy244. Mol Biol Evol. 2019. PMID: 30590616

8

A mechanistic stress model of protein evolution accounts for site-specific evolutionary rates and their relationship with packing density and flexibility.

Huang TT, del Valle Marcos ML, Hwang JK, Echave J. Huang TT, et al. Among authors: echave j. BMC Evol Biol. 2014 Apr 9;14:78. doi: 10.1186/1471-2148-14-78. BMC Evol Biol. 2014. PMID: 24716445 Free PMC article.

9

The variation among sites of protein structure divergence is shaped by mutation and scaled by selection.

Marcos ML, Echave J. Marcos ML, et al. Among authors: echave j. Curr Res Struct Biol. 2020 Aug 26;2:156-163. doi: 10.1016/j.crstbi.2020.08.002. eCollection 2020. Curr Res Struct Biol. 2020. PMID: 34235475 Free PMC article.

10

Evolutionary conservation of protein backbone flexibility.

Maguid S, Fernández-Alberti S, Parisi G, Echave J. Maguid S, et al. Among authors: echave j. J Mol Evol. 2006 Oct;63(4):448-57. doi: 10.1007/s00239-005-0209-x. Epub 2006 Oct 4. J Mol Evol. 2006. PMID: 17021932

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