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GADD45A is a mediator of mitochondrial loss, atrophy, and weakness in skeletal muscle.
Marcotte GR, Miller MJ, Kunz HE, Ryan ZC, Strub MD, Vanderboom PM, Heppelmann CJ, Chau S, Von Ruff ZD, Kilroe SP, McKeen AT, Dierdorff JM, Stern JI, Nath KA, Grueter CE, Lira VA, Judge AR, Rasmussen BB, Nair KS, Lanza IR, Ebert SM, Adams CM. Marcotte GR, et al. Among authors: ebert sm. JCI Insight. 2023 Nov 22;8(22):e171772. doi: 10.1172/jci.insight.171772. JCI Insight. 2023. PMID: 37815864 Free PMC article.
Spermine oxidase maintains basal skeletal muscle gene expression and fiber size and is strongly repressed by conditions that cause skeletal muscle atrophy.
Bongers KS, Fox DK, Kunkel SD, Stebounova LV, Murry DJ, Pufall MA, Ebert SM, Dyle MC, Bullard SA, Dierdorff JM, Adams CM. Bongers KS, et al. Among authors: ebert sm. Am J Physiol Endocrinol Metab. 2015 Jan 15;308(2):E144-58. doi: 10.1152/ajpendo.00472.2014. Epub 2014 Nov 18. Am J Physiol Endocrinol Metab. 2015. PMID: 25406264 Free PMC article.
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