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318 results

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Page 1
Genetic modification of inflammation- and clonal hematopoiesis-associated cardiovascular risk.
Yu Z, Fidler TP, Ruan Y, Vlasschaert C, Nakao T, Uddin MM, Mack T, Niroula A, Heimlich JB, Zekavat SM, Gibson CJ, Griffin GK, Wang Y, Peloso GM, Heard-Costa N, Levy D, Vasan RS, Aguet F, Ardlie KG, Taylor KD, Rich SS, Rotter JI, Libby P, Jaiswal S, Ebert BL, Bick AG, Tall AR, Natarajan P. Yu Z, et al. Among authors: ebert bl. J Clin Invest. 2023 Sep 15;133(18):e168597. doi: 10.1172/JCI168597. J Clin Invest. 2023. PMID: 37498674 Free PMC article.
Increased Risk of Thoracic Aortic Aneurysms With JAK2 V617F.
Nakao T, Yu Z, Vlasschaert C, Uddin MM, Lindsay ME, Ellinor PT, Ebert BL, Bick AG, Pirruccello JP, Natarajan P. Nakao T, et al. Among authors: ebert bl. J Am Coll Cardiol. 2023 May 30;81(21):2128-2130. doi: 10.1016/j.jacc.2023.03.413. J Am Coll Cardiol. 2023. PMID: 37225367 No abstract available.
Clonal haematopoiesis of indeterminate potential predicts incident cardiac arrhythmias.
Schuermans A, Vlasschaert C, Nauffal V, Cho SMJ, Uddin MM, Nakao T, Niroula A, Klarqvist MDR, Weeks LD, Lin AE, Saadatagah S, Lannery K, Wong M, Hornsby W, Lubitz SA, Ballantyne C, Jaiswal S, Libby P, Ebert BL, Bick AG, Ellinor PT, Natarajan P, Honigberg MC. Schuermans A, et al. Among authors: ebert bl. Eur Heart J. 2024 Mar 7;45(10):791-805. doi: 10.1093/eurheartj/ehad670. Eur Heart J. 2024. PMID: 37952204
Atrial Fibrillation and Clonal Hematopoiesis in TET2 and ASXL1.
Saadatagah S, Naderian M, Uddin M, Dikilitas O, Niroula A, Schuermans A, Selvin E, Hoogeveen RC, Matsushita K, Nambi V, Yu B, Chen LY, Bick AG, Ebert BL, Honigberg MC, Li N, Shah A, Natarajan P, Kullo IJ, Ballantyne CM. Saadatagah S, et al. Among authors: ebert bl. JAMA Cardiol. 2024 Apr 10:e240459. doi: 10.1001/jamacardio.2024.0459. Online ahead of print. JAMA Cardiol. 2024. PMID: 38598228
Molecular and clinical presentation of UBA1-mutated myelodysplastic syndromes.
Sirenko M, Bernard E, Creignou M, Domenico D, Farina A, Arango Ossa JE, Kosmider O, Hasserjian RP, Jädersten M, Germing U, Sanz GF, van de Loosdrecht AA, Gurnari C, Follo MY, Thol FR, Zamora L, Pinheiro RF, Pellagatti A, Elias HK, Haase DT, Sander B, Orna E, Zoldan K, Eder LN, Sperr WR, Thalhammer R, Ganster C, Adès L, Tobiasson M, Palomo L, Della Porta MG, Huberman KH, Fenaux P, Belickova M, Savona MR, Klimek V, Santos FPS, Boultwood J, Kotsianidis I, Santini V, Sole F, Platzbecker U, Heuser M, Valent P, Finelli C, Voso MT, Shih LY, Ogawa S, Fontenay M, Jansen JH, Cervera J, Ebert BL, Bejar R, Greenberg PL, Gattermann N, Malcovati L, Cazzola M, Beck DB, Hellstrom-Lindberg ES, Papaemmanuil E. Sirenko M, et al. Among authors: ebert bl. Blood. 2024 Apr 30:blood.2023023723. doi: 10.1182/blood.2023023723. Online ahead of print. Blood. 2024. PMID: 38687605
Targeted protein degradation: from mechanisms to clinic.
Tsai JM, Nowak RP, Ebert BL, Fischer ES. Tsai JM, et al. Among authors: ebert bl. Nat Rev Mol Cell Biol. 2024 Apr 29. doi: 10.1038/s41580-024-00729-9. Online ahead of print. Nat Rev Mol Cell Biol. 2024. PMID: 38684868 Review.
Clonal Hematopoiesis of Indeterminate Potential With Loss of Tet2 Enhances Risk for Atrial Fibrillation Through Nlrp3 Inflammasome Activation.
Lin AE, Bapat AC, Xiao L, Niroula A, Ye J, Wong WJ, Agrawal M, Farady CJ, Boettcher A, Hergott CB, McConkey M, Flores-Bringas P, Shkolnik V, Bick AG, Milan D, Natarajan P, Libby P, Ellinor PT, Ebert BL. Lin AE, et al. Among authors: ebert bl. Circulation. 2024 Apr 30;149(18):1419-1434. doi: 10.1161/CIRCULATIONAHA.123.065597. Epub 2024 Feb 15. Circulation. 2024. PMID: 38357791 Free PMC article.
Targeting the mevalonate or Wnt pathways to overcome CAR T-cell resistance in TP53-mutant AML cells.
Mueller J, Schimmer RR, Koch C, Schneiter F, Fullin J, Lysenko V, Pellegrino C, Klemm N, Russkamp N, Myburgh R, Volta L, Theocharides AP, Kurppa KJ, Ebert BL, Schroeder T, Manz MG, Boettcher S. Mueller J, et al. Among authors: ebert bl. EMBO Mol Med. 2024 Mar;16(3):445-474. doi: 10.1038/s44321-024-00024-2. Epub 2024 Feb 14. EMBO Mol Med. 2024. PMID: 38355749 Free PMC article.
318 results