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Failure of human rhombic lip differentiation underlies medulloblastoma formation.
Hendrikse LD, Haldipur P, Saulnier O, Millman J, Sjoboen AH, Erickson AW, Ong W, Gordon V, Coudière-Morrison L, Mercier AL, Shokouhian M, Suárez RA, Ly M, Borlase S, Scott DS, Vladoiu MC, Farooq H, Sirbu O, Nakashima T, Nambu S, Funakoshi Y, Bahcheli A, Diaz-Mejia JJ, Golser J, Bach K, Phuong-Bao T, Skowron P, Wang EY, Kumar SA, Balin P, Visvanathan A, Lee JJY, Ayoub R, Chen X, Chen X, Mungall KL, Luu B, Bérubé P, Wang YC, Pfister SM, Kim SK, Delattre O, Bourdeaut F, Doz F, Masliah-Planchon J, Grajkowska WA, Loukides J, Dirks P, Fèvre-Montange M, Jouvet A, French PJ, Kros JM, Zitterbart K, Bailey SD, Eberhart CG, Rao AAN, Giannini C, Olson JM, Garami M, Hauser P, Phillips JJ, Ra YS, de Torres C, Mora J, Li KKW, Ng HK, Poon WS, Pollack IF, López-Aguilar E, Gillespie GY, Van Meter TE, Shofuda T, Vibhakar R, Thompson RC, Cooper MK, Rubin JB, Kumabe T, Jung S, Lach B, Iolascon A, Ferrucci V, de Antonellis P, Zollo M, Cinalli G, Robinson S, Stearns DS, Van Meir EG, Porrati P, Finocchiaro G, Massimino M, Carlotti CG, Faria CC, Roussel MF, Boop F, Chan JA, Aldinger KA, Razavi F, Silvestri E, McLendon RE, Thompson EM, Ansari M, Garre ML, Chico F, Eguía P, Pérezpeña M, Morrissy AS, … See abstract for full author list ➔ Hendrikse LD, et al. Among authors: eberhart cg. Nature. 2022 Sep;609(7929):1021-1028. doi: 10.1038/s41586-022-05215-w. Epub 2022 Sep 21. Nature. 2022. PMID: 36131014 Free PMC article.
Medulloblastoma growth inhibition by hedgehog pathway blockade.
Berman DM, Karhadkar SS, Hallahan AR, Pritchard JI, Eberhart CG, Watkins DN, Chen JK, Cooper MK, Taipale J, Olson JM, Beachy PA. Berman DM, et al. Among authors: eberhart cg. Science. 2002 Aug 30;297(5586):1559-61. doi: 10.1126/science.1073733. Science. 2002. PMID: 12202832
The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation.
Uziel T, Zindy F, Xie S, Lee Y, Forget A, Magdaleno S, Rehg JE, Calabrese C, Solecki D, Eberhart CG, Sherr SE, Plimmer S, Clifford SC, Hatten ME, McKinnon PJ, Gilbertson RJ, Curran T, Sherr CJ, Roussel MF. Uziel T, et al. Among authors: eberhart cg. Genes Dev. 2005 Nov 15;19(22):2656-67. doi: 10.1101/gad.1368605. Epub 2005 Oct 31. Genes Dev. 2005. PMID: 16260494 Free PMC article.
c-myc overexpression causes anaplasia in medulloblastoma.
Stearns D, Chaudhry A, Abel TW, Burger PC, Dang CV, Eberhart CG. Stearns D, et al. Among authors: eberhart cg. Cancer Res. 2006 Jan 15;66(2):673-81. doi: 10.1158/0008-5472.CAN-05-1580. Cancer Res. 2006. PMID: 16423996
421 results