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A first-in-human phase I study of MORAb-004, a monoclonal antibody to endosialin in patients with advanced solid tumors.
Diaz LA Jr, Coughlin CM, Weil SC, Fishel J, Gounder MM, Lawrence S, Azad N, O'Shannessy DJ, Grasso L, Wustner J, Ebel W, Carvajal RD. Diaz LA Jr, et al. Among authors: ebel w. Clin Cancer Res. 2015 Mar 15;21(6):1281-8. doi: 10.1158/1078-0432.CCR-14-1829. Epub 2014 Nov 14. Clin Cancer Res. 2015. PMID: 25398449 Free PMC article. Clinical Trial.
Developing novel biopharmaceutical products through morphogenics.
Nicolaides NC, Sass PM, Chao Q, Kline JB, Ebel W, Routhier E, Zhou Y, Grasso L. Nicolaides NC, et al. Among authors: ebel w. Expert Opin Drug Discov. 2007 Dec;2(12):1619-29. doi: 10.1517/17460441.2.12.1619. Expert Opin Drug Discov. 2007. PMID: 23488905
Human antibodies for immunotherapy development generated via a human B cell hybridoma technology.
Li J, Sai T, Berger M, Chao Q, Davidson D, Deshmukh G, Drozdowski B, Ebel W, Harley S, Henry M, Jacob S, Kline B, Lazo E, Rotella F, Routhier E, Rudolph K, Sage J, Simon P, Yao J, Zhou Y, Kavuru M, Bonfield T, Thomassen MJ, Sass PM, Nicolaides NC, Grasso L. Li J, et al. Among authors: ebel w. Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3557-62. doi: 10.1073/pnas.0511285103. Epub 2006 Feb 27. Proc Natl Acad Sci U S A. 2006. PMID: 16505368 Free PMC article.
Morphogenics as a tool for target discovery and drug development.
Nicolaides NC, Ebel W, Kline B, Chao Q, Routhier E, Sass PM, Grasso L. Nicolaides NC, et al. Among authors: ebel w. Ann N Y Acad Sci. 2005 Nov;1059:86-96. doi: 10.1196/annals.1339.029. Ann N Y Acad Sci. 2005. PMID: 16382047 Review.
20 results