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Measuring Kinase Activity-A Global Challenge.
Cann ML, McDonald IM, East MP, Johnson GL, Graves LM. Cann ML, et al. Among authors: east mp. J Cell Biochem. 2017 Nov;118(11):3595-3606. doi: 10.1002/jcb.26103. Epub 2017 May 31. J Cell Biochem. 2017. PMID: 28464261 Review.
BIRC6 mediates imatinib resistance independently of Mcl-1.
Okumu DO, East MP, Levine M, Herring LE, Zhang R, Gilbert TSK, Litchfield DW, Zhang Y, Graves LM. Okumu DO, et al. Among authors: east mp. PLoS One. 2017 May 16;12(5):e0177871. doi: 10.1371/journal.pone.0177871. eCollection 2017. PLoS One. 2017. PMID: 28520795 Free PMC article.
Proteomic analysis defines kinase taxonomies specific for subtypes of breast cancer.
Collins KAL, Stuhlmiller TJ, Zawistowski JS, East MP, Pham TT, Hall CR, Goulet DR, Bevill SM, Angus SP, Velarde SH, Sciaky N, Oprea TI, Graves LM, Johnson GL, Gomez SM. Collins KAL, et al. Among authors: east mp. Oncotarget. 2018 Jan 29;9(21):15480-15497. doi: 10.18632/oncotarget.24337. eCollection 2018 Mar 20. Oncotarget. 2018. PMID: 29643987 Free PMC article.
Application of Integrated Drug Screening/Kinome Analysis to Identify Inhibitors of Gemcitabine-Resistant Pancreatic Cancer Cell Growth.
Krulikas LJ, McDonald IM, Lee B, Okumu DO, East MP, Gilbert TSK, Herring LE, Golitz BT, Wells CI, Axtman AD, Zuercher WJ, Willson TM, Kireev D, Yeh JJ, Johnson GL, Baines AT, Graves LM. Krulikas LJ, et al. Among authors: east mp. SLAS Discov. 2018 Sep;23(8):850-861. doi: 10.1177/2472555218773045. Epub 2018 May 9. SLAS Discov. 2018. PMID: 29742358 Free PMC article.
Mitochondrial Protease ClpP is a Target for the Anticancer Compounds ONC201 and Related Analogues.
Graves PR, Aponte-Collazo LJ, Fennell EMJ, Graves AC, Hale AE, Dicheva N, Herring LE, Gilbert TSK, East MP, McDonald IM, Lockett MR, Ashamalla H, Moorman NJ, Karanewsky DS, Iwanowicz EJ, Holmuhamedov E, Graves LM. Graves PR, et al. Among authors: east mp. ACS Chem Biol. 2019 May 17;14(5):1020-1029. doi: 10.1021/acschembio.9b00222. Epub 2019 May 1. ACS Chem Biol. 2019. PMID: 31021596 Free PMC article.
Lyn regulates creatine uptake in an imatinib-resistant CML cell line.
Okumu DO, Aponte-Collazo LJ, Dewar BJ, Cox NJ, East MP, Tech K, McDonald IM, Tikunov AP, Holmuhamedov E, Macdonald JM, Graves LM. Okumu DO, et al. Among authors: east mp. Biochim Biophys Acta Gen Subj. 2020 Apr;1864(4):129507. doi: 10.1016/j.bbagen.2019.129507. Epub 2019 Dec 24. Biochim Biophys Acta Gen Subj. 2020. PMID: 31881245 Free PMC article.
Mass spectrometry-based selectivity profiling identifies a highly selective inhibitor of the kinase MELK that delays mitotic entry in cancer cells.
McDonald IM, Grant GD, East MP, Gilbert TSK, Wilkerson EM, Goldfarb D, Beri J, Herring LE, Vaziri C, Cook JG, Emanuele MJ, Graves LM. McDonald IM, et al. Among authors: east mp. J Biol Chem. 2020 Feb 21;295(8):2359-2374. doi: 10.1074/jbc.RA119.011083. Epub 2020 Jan 2. J Biol Chem. 2020. PMID: 31896573 Free PMC article.
43 results