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Page 1
A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms.
Ménard D, Khim N, Beghain J, Adegnika AA, Shafiul-Alam M, Amodu O, Rahim-Awab G, Barnadas C, Berry A, Boum Y, Bustos MD, Cao J, Chen JH, Collet L, Cui L, Thakur GD, Dieye A, Djallé D, Dorkenoo MA, Eboumbou-Moukoko CE, Espino FE, Fandeur T, Ferreira-da-Cruz MF, Fola AA, Fuehrer HP, Hassan AM, Herrera S, Hongvanthong B, Houzé S, Ibrahim ML, Jahirul-Karim M, Jiang L, Kano S, Ali-Khan W, Khanthavong M, Kremsner PG, Lacerda M, Leang R, Leelawong M, Li M, Lin K, Mazarati JB, Ménard S, Morlais I, Muhindo-Mavoko H, Musset L, Na-Bangchang K, Nambozi M, Niaré K, Noedl H, Ouédraogo JB, Pillai DR, Pradines B, Quang-Phuc B, Ramharter M, Randrianarivelojosia M, Sattabongkot J, Sheikh-Omar A, Silué KD, Sirima SB, Sutherland C, Syafruddin D, Tahar R, Tang LH, Touré OA, Tshibangu-wa-Tshibangu P, Vigan-Womas I, Warsame M, Wini L, Zakeri S, Kim S, Eam R, Berne L, Khean C, Chy S, Ken M, Loch K, Canier L, Duru V, Legrand E, Barale JC, Stokes B, Straimer J, Witkowski B, Fidock DA, Rogier C, Ringwald P, Ariey F, Mercereau-Puijalon O; KARMA Consortium. Ménard D, et al. Among authors: eam r. N Engl J Med. 2016 Jun 23;374(25):2453-64. doi: 10.1056/NEJMoa1513137. N Engl J Med. 2016. PMID: 27332904 Free PMC article.
Plasmodium falciparum dihydroartemisinin-piperaquine failures in Cambodia are associated with mutant K13 parasites presenting high survival rates in novel piperaquine in vitro assays: retrospective and prospective investigations.
Duru V, Khim N, Leang R, Kim S, Domergue A, Kloeung N, Ke S, Chy S, Eam R, Khean C, Loch K, Ken M, Lek D, Beghain J, Ariey F, Guerin PJ, Huy R, Mercereau-Puijalon O, Witkowski B, Menard D. Duru V, et al. Among authors: eam r. BMC Med. 2015 Dec 22;13:305. doi: 10.1186/s12916-015-0539-5. BMC Med. 2015. PMID: 26695060 Free PMC article.
A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype-genotype association study.
Witkowski B, Duru V, Khim N, Ross LS, Saintpierre B, Beghain J, Chy S, Kim S, Ke S, Kloeung N, Eam R, Khean C, Ken M, Loch K, Bouillon A, Domergue A, Ma L, Bouchier C, Leang R, Huy R, Nuel G, Barale JC, Legrand E, Ringwald P, Fidock DA, Mercereau-Puijalon O, Ariey F, Ménard D. Witkowski B, et al. Among authors: eam r. Lancet Infect Dis. 2017 Feb;17(2):174-183. doi: 10.1016/S1473-3099(16)30415-7. Epub 2016 Nov 3. Lancet Infect Dis. 2017. PMID: 27818097 Free PMC article.
A novel field-based molecular assay to detect validated artemisinin-resistant k13 mutants.
Vachot-Ganée L, Khim N, Iannello A, Legrand E, Kim S, Eam R, Khean C, Ken M, Ashley E, Tun KM, Dhorda M, Nosten F, Souleymane IM, Blein S, Pachot A, Ariey F, Kaiser K, Ménard D. Vachot-Ganée L, et al. Among authors: eam r. Malar J. 2018 Apr 24;17(1):175. doi: 10.1186/s12936-018-2329-y. Malar J. 2018. PMID: 29690890 Free PMC article.
In vitro activity of ferroquine against artemisinin-based combination therapy (ACT)-resistant Plasmodium falciparum isolates from Cambodia.
Mairet-Khedim M, Nardella F, Khim N, Kim S, Kloeung N, Ke S, Kauy C, Eam R, Khean C, Pellet A, Leboulleux D, Leang R, Ringwald P, Barale JC, Leroy D, Menard D, Witkowski B. Mairet-Khedim M, et al. Among authors: eam r. J Antimicrob Chemother. 2019 Nov 1;74(11):3240-3244. doi: 10.1093/jac/dkz340. J Antimicrob Chemother. 2019. PMID: 31518407
Malaria PCR detection in Cambodian low-transmission settings: dried blood spots versus venous blood samples.
Canier L, Khim N, Kim S, Eam R, Khean C, Loch K, Ken M, Pannus P, Bosman P, Stassijns J, Nackers F, Alipon S, Char MC, Chea N, Etienne W, De Smet M, Kindermans JM, Ménard D. Canier L, et al. Among authors: eam r. Am J Trop Med Hyg. 2015 Mar;92(3):573-7. doi: 10.4269/ajtmh.14-0614. Epub 2015 Jan 5. Am J Trop Med Hyg. 2015. PMID: 25561570 Free PMC article.
Closing in on the Reservoir: Proactive Case Detection in High-Risk Groups as a Strategy to Detect Plasmodium falciparum Asymptomatic Carriers in Cambodia.
Rossi G, Vernaeve L, Van den Bergh R, Nguon C, Debackere M, Abello Peiri C, Van V, Khim N, Kim S, Eam R, Ken M, Khean C, De Smet M, Menard D, Kindermans JM. Rossi G, et al. Among authors: eam r. Clin Infect Dis. 2018 May 2;66(10):1610-1617. doi: 10.1093/cid/cix1064. Clin Infect Dis. 2018. PMID: 29361021
An innovative tool for moving malaria PCR detection of parasite reservoir into the field.
Canier L, Khim N, Kim S, Sluydts V, Heng S, Dourng D, Eam R, Chy S, Khean C, Loch K, Ken M, Lim H, Siv S, Tho S, Masse-Navette P, Gryseels C, Uk S, Van Roey K, Grietens KP, Sokny M, Thavrin B, Chuor CM, Deubel V, Durnez L, Coosemans M, Ménard D. Canier L, et al. Among authors: eam r. Malar J. 2013 Nov 9;12:405. doi: 10.1186/1475-2875-12-405. Malar J. 2013. PMID: 24206649 Free PMC article.
Prevalence and characterization of piperaquine, mefloquine and artemisinin derivatives triple-resistant Plasmodium falciparum in Cambodia.
Mairet-Khedim M, Roesch C, Khim N, Srun S, Bouillon A, Kim S, Ke S, Kauy C, Kloeung N, Eam R, Khean C, Kul C, Chy S, Leang R, Ringwald P, Barale JC, Witkowski B. Mairet-Khedim M, et al. Among authors: eam r. J Antimicrob Chemother. 2023 Feb 1;78(2):411-417. doi: 10.1093/jac/dkac403. J Antimicrob Chemother. 2023. PMID: 36508338 Free PMC article.