Eadsforth TC - Search Results

1

Structure and mechanism of imidazoleglycerol-phosphate dehydratase.

Glynn SE, Baker PJ, Sedelnikova SE, Davies CL, Eadsforth TC, Levy CW, Rodgers HF, Blackburn GM, Hawkes TR, Viner R, Rice DW. Glynn SE, et al. Among authors: eadsforth tc. Structure. 2005 Dec;13(12):1809-17. doi: 10.1016/j.str.2005.08.012. Structure. 2005. PMID: 16338409 Free article.

2

Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.

Bisson C, Britton KL, Sedelnikova SE, Rodgers HF, Eadsforth TC, Viner RC, Hawkes TR, Baker PJ, Rice DW. Bisson C, et al. Among authors: eadsforth tc. Structure. 2015 Jul 7;23(7):1236-45. doi: 10.1016/j.str.2015.05.012. Epub 2015 Jun 18. Structure. 2015. PMID: 26095028 Free PMC article.

3

Mirror-Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide.

Bisson C, Britton KL, Sedelnikova SE, Rodgers HF, Eadsforth TC, Viner RC, Hawkes TR, Baker PJ, Rice DW. Bisson C, et al. Among authors: eadsforth tc. Angew Chem Int Ed Engl. 2016 Oct 17;55(43):13485-13489. doi: 10.1002/anie.201607185. Epub 2016 Sep 26. Angew Chem Int Ed Engl. 2016. PMID: 27717128 Free PMC article.

4

Pseudomonas aeruginosa 4-amino-4-deoxychorismate lyase: spatial conservation of an active site tyrosine and classification of two types of enzyme.

O'Rourke PE, Eadsforth TC, Fyfe PK, Shepherd SM, Hunter WN. O'Rourke PE, et al. Among authors: eadsforth tc. PLoS One. 2011;6(9):e24158. doi: 10.1371/journal.pone.0024158. Epub 2011 Sep 15. PLoS One. 2011. PMID: 21935381 Free PMC article.

5

Structure of the SCAN domain of human paternally expressed gene 3 protein.

Rimsa V, Eadsforth TC, Hunter WN. Rimsa V, et al. Among authors: eadsforth tc. PLoS One. 2013 Jul 23;8(7):e69538. doi: 10.1371/journal.pone.0069538. Print 2013. PLoS One. 2013. PMID: 23936039 Free PMC article.

6

Acinetobacter baumannii FolD ligand complexes --potent inhibitors of folate metabolism and a re-evaluation of the structure of LY374571.

Eadsforth TC, Maluf FV, Hunter WN. Eadsforth TC, et al. FEBS J. 2012 Dec;279(23):4350-60. doi: 10.1111/febs.12025. Epub 2012 Nov 5. FEBS J. 2012. PMID: 23050773 Free PMC article.

7

High-resolution structure of the M14-type cytosolic carboxypeptidase from Burkholderia cenocepacia refined exploiting PDB_REDO strategies.

Rimsa V, Eadsforth TC, Joosten RP, Hunter WN. Rimsa V, et al. Among authors: eadsforth tc. Acta Crystallogr D Biol Crystallogr. 2014 Feb;70(Pt 2):279-89. doi: 10.1107/S1399004713026801. Epub 2014 Jan 29. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 24531462 Free PMC article.

8

The role of Co²+ in the crystallization of human SENP1 and comments on the limitations of automated refinement protocols.

Rimsa V, Eadsforth T, Hunter WN. Rimsa V, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Apr 1;67(Pt 4):442-5. doi: 10.1107/S1744309111005835. Epub 2011 Mar 24. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 21505236 Free PMC article.

9

Characterization of 2,4-Diamino-6-oxo-1,6-dihydropyrimidin-5-yl Ureido Based Inhibitors of Trypanosoma brucei FolD and Testing for Antiparasitic Activity.

Eadsforth TC, Pinto A, Luciani R, Tamborini L, Cullia G, De Micheli C, Marinelli L, Cosconati S, Novellino E, Lo Presti L, Cordeiro da Silva A, Conti P, Hunter WN, Costi MP. Eadsforth TC, et al. J Med Chem. 2015 Oct 22;58(20):7938-48. doi: 10.1021/acs.jmedchem.5b00687. Epub 2015 Sep 16. J Med Chem. 2015. PMID: 26322631 Free PMC article.

10

Identification of Leishmania major UDP-Sugar Pyrophosphorylase Inhibitors Using Biosensor-Based Small Molecule Fragment Library Screening.

Prakash O, Führing J, Post J, Shepherd SM, Eadsforth TC, Gray D, Fedorov R, Routier FH. Prakash O, et al. Among authors: eadsforth tc. Molecules. 2019 Mar 12;24(5):996. doi: 10.3390/molecules24050996. Molecules. 2019. PMID: 30871023 Free PMC article.

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