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Megalin binds and internalizes angiotensin-(1-7).
Gonzalez-Villalobos R, Klassen RB, Allen PL, Johanson K, Baker CB, Kobori H, Navar LG, Hammond TG. Gonzalez-Villalobos R, et al. Am J Physiol Renal Physiol. 2006 May;290(5):F1270-5. doi: 10.1152/ajprenal.00164.2005. Epub 2005 Dec 27. Am J Physiol Renal Physiol. 2006. PMID: 16380466 Free PMC article.
Megalin binds and internalizes angiotensin II.
Gonzalez-Villalobos R, Klassen RB, Allen PL, Navar LG, Hammond TG. Gonzalez-Villalobos R, et al. Am J Physiol Renal Physiol. 2005 Feb;288(2):F420-7. doi: 10.1152/ajprenal.00243.2004. Epub 2004 Oct 5. Am J Physiol Renal Physiol. 2005. PMID: 15467006 Free article.
Light chains are a ligand for megalin.
Klassen RB, Allen PL, Batuman V, Crenshaw K, Hammond TG. Klassen RB, et al. J Appl Physiol (1985). 2005 Jan;98(1):257-63. doi: 10.1152/japplphysiol.01090.2003. Epub 2004 Jul 30. J Appl Physiol (1985). 2005. PMID: 15286052 Free article.
Megalin mediates renal uptake of heavy metal metallothionein complexes.
Klassen RB, Crenshaw K, Kozyraki R, Verroust PJ, Tio L, Atrian S, Allen PL, Hammond TG. Klassen RB, et al. Am J Physiol Renal Physiol. 2004 Sep;287(3):F393-403. doi: 10.1152/ajprenal.00233.2003. Epub 2004 May 4. Am J Physiol Renal Physiol. 2004. PMID: 15126248 Free article.