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Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy.
Logue SE, McGrath EP, Cleary P, Greene S, Mnich K, Almanza A, Chevet E, Dwyer RM, Oommen A, Legembre P, Godey F, Madden EC, Leuzzi B, Obacz J, Zeng Q, Patterson JB, Jäger R, Gorman AM, Samali A. Logue SE, et al. Among authors: dwyer rm. Nat Commun. 2018 Aug 15;9(1):3267. doi: 10.1038/s41467-018-05763-8. Nat Commun. 2018. PMID: 30111846 Free PMC article.
Employing mesenchymal stem cells to support tumor-targeted delivery of extracellular vesicle (EV)-encapsulated microRNA-379.
O'Brien KP, Khan S, Gilligan KE, Zafar H, Lalor P, Glynn C, O'Flatharta C, Ingoldsby H, Dockery P, De Bhulbh A, Schweber JR, St John K, Leahy M, Murphy JM, Gallagher WM, O'Brien T, Kerin MJ, Dwyer RM. O'Brien KP, et al. Among authors: dwyer rm. Oncogene. 2018 Apr;37(16):2137-2149. doi: 10.1038/s41388-017-0116-9. Epub 2018 Jan 25. Oncogene. 2018. PMID: 29367765
Engineering Exosomes for Cancer Therapy.
Gilligan KE, Dwyer RM. Gilligan KE, et al. Among authors: dwyer rm. Int J Mol Sci. 2017 May 24;18(6):1122. doi: 10.3390/ijms18061122. Int J Mol Sci. 2017. PMID: 28538671 Free PMC article. Review.
Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: stimulation of epithelial to mesenchymal transition (EMT).
Martin FT, Dwyer RM, Kelly J, Khan S, Murphy JM, Curran C, Miller N, Hennessy E, Dockery P, Barry FP, O'Brien T, Kerin MJ. Martin FT, et al. Among authors: dwyer rm. Breast Cancer Res Treat. 2010 Nov;124(2):317-26. doi: 10.1007/s10549-010-0734-1. Epub 2010 Jan 20. Breast Cancer Res Treat. 2010. PMID: 20087650
109 results