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The C-terminal peptide of CCL21 drastically augments CCL21 activity through the dendritic cell lymph node homing receptor CCR7 by interaction with the receptor N-terminus.
Jørgensen AS, Brandum EP, Mikkelsen JM, Orfin KA, Boilesen DR, Egerod KL, Moussouras NA, Vilhardt F, Kalinski P, Basse P, Chen YH, Yang Z, Dwinell MB, Volkman BF, Veldkamp CT, Holst PJ, Lahl K, Goth CK, Rosenkilde MM, Hjortø GM. Jørgensen AS, et al. Among authors: dwinell mb. Cell Mol Life Sci. 2021 Nov;78(21-22):6963-6978. doi: 10.1007/s00018-021-03930-7. Epub 2021 Sep 29. Cell Mol Life Sci. 2021. PMID: 34586443 Free PMC article.
Chemokines in colitis: microRNA control.
Roy I, Veldkamp CT, Volkman BF, Dwinell MB. Roy I, et al. Among authors: dwinell mb. Gut. 2014 Aug;63(8):1202-4. doi: 10.1136/gutjnl-2013-305886. Epub 2013 Oct 18. Gut. 2014. PMID: 24142964 Free PMC article. No abstract available.
Structural basis for chemokine recognition by a G protein-coupled receptor and implications for receptor activation.
Ziarek JJ, Kleist AB, London N, Raveh B, Montpas N, Bonneterre J, St-Onge G, DiCosmo-Ponticello CJ, Koplinski CA, Roy I, Stephens B, Thelen S, Veldkamp CT, Coffman FD, Cohen MC, Dwinell MB, Thelen M, Peterson FC, Heveker N, Volkman BF. Ziarek JJ, et al. Among authors: dwinell mb. Sci Signal. 2017 Mar 21;10(471):eaah5756. doi: 10.1126/scisignal.aah5756. Sci Signal. 2017. PMID: 28325822 Free PMC article.
CCR7 Sulfotyrosine Enhances CCL21 Binding.
Phillips AJ, Taleski D, Koplinski CA, Getschman AE, Moussouras NA, Richard AM, Peterson FC, Dwinell MB, Volkman BF, Payne RJ, Veldkamp CT. Phillips AJ, et al. Among authors: dwinell mb. Int J Mol Sci. 2017 Aug 25;18(9):1857. doi: 10.3390/ijms18091857. Int J Mol Sci. 2017. PMID: 28841151 Free PMC article.
Targeted biologic inhibition of both tumor cell-intrinsic and intercellular CLPTM1L/CRR9-mediated chemotherapeutic drug resistance.
Parashar D, Geethadevi A, McAllister D, Ebben J, Peterson FC, Jensen DR, Bishop E, Pradeep S, Volkman BF, Dwinell MB, Chaluvally-Raghavan P, James MA. Parashar D, et al. Among authors: dwinell mb. NPJ Precis Oncol. 2021 Mar 2;5(1):16. doi: 10.1038/s41698-021-00152-9. NPJ Precis Oncol. 2021. PMID: 33654182 Free PMC article.
89 results