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The novel non-hallucinogenic compound DM506 (3-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole) induces sedative- and anxiolytic-like activity in mice by a mechanism involving 5-HT2A receptor activation.
Arias HR, Rudin D, Hines DJ, Contreras A, Gulsevin A, Manetti D, Anouar Y, De Deurwaerdere P, Meiler J, Romanelli MN, Liechti ME, Chagraoui A. Arias HR, et al. Among authors: hines dj. Eur J Pharmacol. 2024 Mar 5;966:176329. doi: 10.1016/j.ejphar.2024.176329. Epub 2024 Jan 20. Eur J Pharmacol. 2024. PMID: 38253116
TSPO regulation in reactive gliotic diseases.
McNeela AM, Bernick C, Hines RM, Hines DJ. McNeela AM, et al. Among authors: hines dj. J Neurosci Res. 2018 Jun;96(6):978-988. doi: 10.1002/jnr.24212. Epub 2018 Jan 6. J Neurosci Res. 2018. PMID: 29315754 Review.
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