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TRYBE®: an Fc-free antibody format with three monovalent targeting arms engineered for long in vivo half-life.
MAbs. 2023 Jan-Dec;15(1):2160229. doi: 10.1080/19420862.2022.2160229.
MAbs. 2023.
PMID: 36788124
Free PMC article.
Drug-like antibodies with high affinity, diversity and developability directly from next-generation antibody libraries.
Azevedo Reis Teixeira A, Erasmus MF, D'Angelo S, Naranjo L, Ferrara F, Leal-Lopes C, Durrant O, Galmiche C, Morelli A, Scott-Tucker A, Bradbury ARM.
Azevedo Reis Teixeira A, et al. Among authors: durrant o.
MAbs. 2021 Jan-Dec;13(1):1980942. doi: 10.1080/19420862.2021.1980942.
MAbs. 2021.
PMID: 34850665
Free PMC article.
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A Conformational Change of Complement C5 Is Required for Thrombin-Mediated Cleavage, Revealed by a Novel Ex Vivo Human Whole Blood Model Preserving Full Thrombin Activity.
Nilsson PH, Johnson C, Quach QH, Macpherson A, Durrant O, Pischke SE, Fure H, Landsem A, Bergseth G, Schjalm C, Haugaard-Kedström LM, Huber-Lang M, van den Elsen J, Brekke OL, Mollnes TE.
Nilsson PH, et al. Among authors: durrant o.
J Immunol. 2021 Sep 15;207(6):1641-1651. doi: 10.4049/jimmunol.2001471. Epub 2021 Aug 11.
J Immunol. 2021.
PMID: 34380648
Free PMC article.
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Reference Protocol to Assess Analytical Performance of Higher Order Structural Analysis Measurements: Results from an Interlaboratory Comparison.
Groves K, Ashcroft AE, Cryar A, Sula A, Wallace BA, Stocks BB, Burns C, Cooper-Shepherd D, De Lorenzi E, Rodriguez E, Zhang H, Ault JR, Ferguson J, Phillips JJ, Pacholarz K, Thalassinos K, Luckau L, Ashton L, Durrant O, Barran P, Dalby P, Vicedo P, Colombo R, Davis R, Parakra R, Upton R, Hill S, Wood V, Soloviev Z, Quaglia M.
Groves K, et al. Among authors: durrant o.
Anal Chem. 2021 Jul 6;93(26):9041-9048. doi: 10.1021/acs.analchem.0c04625. Epub 2021 Jun 24.
Anal Chem. 2021.
PMID: 34165299
Free article.
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The rational design of affinity-attenuated OmCI for the purification of complement C5.
Macpherson A, Liu X, Dedi N, Kennedy J, Carrington B, Durrant O, Heywood S, van den Elsen J, Lawson ADG.
Macpherson A, et al. Among authors: durrant o.
J Biol Chem. 2018 Sep 7;293(36):14112-14121. doi: 10.1074/jbc.RA118.004043. Epub 2018 Jul 20.
J Biol Chem. 2018.
PMID: 30030376
Free PMC article.
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