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JMJD6 promotes self-renewal and regenerative capacity of hematopoietic stem cells.
Blood Adv. 2021 Feb 9;5(3):889-899. doi: 10.1182/bloodadvances.2020002702.
Blood Adv. 2021.
PMID: 33560400
Free PMC article.
The mRNA m6A reader YTHDF2 suppresses proinflammatory pathways and sustains hematopoietic stem cell function.
Mapperley C, van de Lagemaat LN, Lawson H, Tavosanis A, Paris J, Campos J, Wotherspoon D, Durko J, Sarapuu A, Choe J, Ivanova I, Krause DS, von Kriegsheim A, Much C, Morgan M, Gregory RI, Mead AJ, O'Carroll D, Kranc KR.
Mapperley C, et al. Among authors: durko j.
J Exp Med. 2021 Mar 1;218(3):e20200829. doi: 10.1084/jem.20200829.
J Exp Med. 2021.
PMID: 33156926
Free PMC article.
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CITED2 coordinates key hematopoietic regulatory pathways to maintain the HSC pool in both steady-state hematopoiesis and transplantation.
Lawson H, van de Lagemaat LN, Barile M, Tavosanis A, Durko J, Villacreces A, Bellani A, Mapperley C, Georges E, Martins-Costa C, Sepulveda C, Allen L, Campos J, Campbell KJ, O'Carroll D, Göttgens B, Cory S, Rodrigues NP, Guitart AV, Kranc KR.
Lawson H, et al. Among authors: durko j.
Stem Cell Reports. 2021 Nov 9;16(11):2784-2797. doi: 10.1016/j.stemcr.2021.10.001. Epub 2021 Oct 28.
Stem Cell Reports. 2021.
PMID: 34715054
Free PMC article.
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The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia.
Lawson H, Holt-Martyn JP, Dembitz V, Kabayama Y, Wang LM, Bellani A, Atwal S, Saffoon N, Durko J, van de Lagemaat LN, De Pace AL, Tumber A, Corner T, Salah E, Arndt C, Brewitz L, Bowen M, Dubusse L, George D, Allen L, Guitart AV, Fung TK, So CWE, Schwaller J, Gallipoli P, O'Carroll D, Schofield CJ, Kranc KR.
Lawson H, et al. Among authors: durko j.
Nat Cancer. 2024 Apr 18. doi: 10.1038/s43018-024-00761-w. Online ahead of print.
Nat Cancer. 2024.
PMID: 38637657
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Immunodeficient NBSGW mouse strain allows chemotherapy modeling in AML patient-derived xenografts.
Dembitz V, Durko J, Campos J, James SC, Lawson H, Kranc KR, Gallipoli P.
Dembitz V, et al. Among authors: durko j.
Hemasphere. 2024 Jan 27;8(1):e28. doi: 10.1002/hem3.28. eCollection 2024 Jan.
Hemasphere. 2024.
PMID: 38434525
Free PMC article.
No abstract available.
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