Durek T - Search Results

1

Low potency inhibition of Na_V1.7 by externally applied QX-314 via a depolarizing shift in the voltage-dependence of activation.

Klasfauseweh T, Israel MR, Ragnarsson L, Cox JJ, Durek T, Carter DA, Leffler A, Vetter I, Deuis JR. Klasfauseweh T, et al. Among authors: durek t. Eur J Pharmacol. 2022 Jun 15;925:175013. doi: 10.1016/j.ejphar.2022.175013. Epub 2022 May 7. Eur J Pharmacol. 2022. PMID: 35537491

2

Chemical synthesis and structure of the prokineticin Bv8.

Morales RA, Daly NL, Vetter I, Mobli M, Napier IA, Craik DJ, Lewis RJ, Christie MJ, King GF, Alewood PF, Durek T. Morales RA, et al. Among authors: durek t. Chembiochem. 2010 Sep 3;11(13):1882-8. doi: 10.1002/cbic.201000330. Chembiochem. 2010. PMID: 20677202

3

Characterisation of Na(v) types endogenously expressed in human SH-SY5Y neuroblastoma cells.

Vetter I, Mozar CA, Durek T, Wingerd JS, Alewood PF, Christie MJ, Lewis RJ. Vetter I, et al. Among authors: durek t. Biochem Pharmacol. 2012 Jun 1;83(11):1562-71. doi: 10.1016/j.bcp.2012.02.022. Epub 2012 Mar 3. Biochem Pharmacol. 2012. PMID: 22410003

4

Chemical engineering and structural and pharmacological characterization of the α-scorpion toxin OD1.

Durek T, Vetter I, Wang CI, Motin L, Knapp O, Adams DJ, Lewis RJ, Alewood PF. Durek T, et al. ACS Chem Biol. 2013;8(6):1215-22. doi: 10.1021/cb400012k. Epub 2013 Apr 3. ACS Chem Biol. 2013. PMID: 23527544

5

Isolation and structural and pharmacological characterization of α-elapitoxin-Dpp2d, an amidated three finger toxin from black mamba venom.

Wang CI, Reeks T, Vetter I, Vergara I, Kovtun O, Lewis RJ, Alewood PF, Durek T. Wang CI, et al. Among authors: durek t. Biochemistry. 2014 Jun 17;53(23):3758-66. doi: 10.1021/bi5004475. Epub 2014 Jun 5. Biochemistry. 2014. PMID: 24867092

6

Analgesic Effects of GpTx-1, PF-04856264 and CNV1014802 in a Mouse Model of NaV1.7-Mediated Pain.

Deuis JR, Wingerd JS, Winter Z, Durek T, Dekan Z, Sousa SR, Zimmermann K, Hoffmann T, Weidner C, Nassar MA, Alewood PF, Lewis RJ, Vetter I. Deuis JR, et al. Among authors: durek t. Toxins (Basel). 2016 Mar 17;8(3):78. doi: 10.3390/toxins8030078. Toxins (Basel). 2016. PMID: 26999206 Free PMC article.

7

The E15R Point Mutation in Scorpion Toxin Cn2 Uncouples Its Depressant and Excitatory Activities on Human Na_V1.6.

Israel MR, Thongyoo P, Deuis JR, Craik DJ, Vetter I, Durek T. Israel MR, et al. Among authors: durek t. J Med Chem. 2018 Feb 22;61(4):1730-1736. doi: 10.1021/acs.jmedchem.7b01609. Epub 2018 Feb 3. J Med Chem. 2018. PMID: 29378414

8

A Centipede Toxin Family Defines an Ancient Class of CSαβ Defensins.

Dash TS, Shafee T, Harvey PJ, Zhang C, Peigneur S, Deuis JR, Vetter I, Tytgat J, Anderson MA, Craik DJ, Durek T, Undheim EAB. Dash TS, et al. Among authors: durek t. Structure. 2019 Feb 5;27(2):315-326.e7. doi: 10.1016/j.str.2018.10.022. Epub 2018 Dec 13. Structure. 2019. PMID: 30554841 Free article.

9

Na_V 1.6 regulates excitability of mechanosensitive sensory neurons.

Israel MR, Tanaka BS, Castro J, Thongyoo P, Robinson SD, Zhao P, Deuis JR, Craik DJ, Durek T, Brierley SM, Waxman SG, Dib-Hajj SD, Vetter I. Israel MR, et al. Among authors: durek t. J Physiol. 2019 Jul;597(14):3751-3768. doi: 10.1113/JP278148. Epub 2019 May 13. J Physiol. 2019. PMID: 31087362 Free article.

10

Characterization of Synthetic Tf2 as a Na_V1.3 Selective Pharmacological Probe.

Israel MR, Dash TS, Bothe SN, Robinson SD, Deuis JR, Craik DJ, Lampert A, Vetter I, Durek T. Israel MR, et al. Among authors: durek t. Biomedicines. 2020 Jun 11;8(6):155. doi: 10.3390/biomedicines8060155. Biomedicines. 2020. PMID: 32545167 Free PMC article.

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