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Hyaluronan driven by epithelial aPKC deficiency remodels the microenvironment and creates a vulnerability in mesenchymal colorectal cancer.
Martinez-Ordoñez A, Duran A, Ruiz-Martinez M, Cid-Diaz T, Zhang X, Han Q, Kinoshita H, Muta Y, Linares JF, Kasashima H, Nakanishi Y, Omar M, Nishimura S, Avila L, Yashiro M, Maeda K, Pannellini T, Pigazzi A, Inghirami G, Marchionni L, Sigal D, Diaz-Meco MT, Moscat J. Martinez-Ordoñez A, et al. Among authors: duran a. Cancer Cell. 2023 Feb 13;41(2):252-271.e9. doi: 10.1016/j.ccell.2022.11.016. Epub 2022 Dec 15. Cancer Cell. 2023. PMID: 36525970 Free PMC article.
Par-4 inhibits Akt and suppresses Ras-induced lung tumorigenesis.
Joshi J, Fernandez-Marcos PJ, Galvez A, Amanchy R, Linares JF, Duran A, Pathrose P, Leitges M, Cañamero M, Collado M, Salas C, Serrano M, Moscat J, Diaz-Meco MT. Joshi J, et al. Among authors: duran a. EMBO J. 2008 Aug 20;27(16):2181-93. doi: 10.1038/emboj.2008.149. Epub 2008 Jul 24. EMBO J. 2008. PMID: 18650932 Free PMC article.
Atypical protein kinase C (aPKCzeta and aPKClambda) is dispensable for mammalian hematopoietic stem cell activity and blood formation.
Sengupta A, Duran A, Ishikawa E, Florian MC, Dunn SK, Ficker AM, Leitges M, Geiger H, Diaz-Meco M, Moscat J, Cancelas JA. Sengupta A, et al. Among authors: duran a. Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):9957-62. doi: 10.1073/pnas.1103132108. Epub 2011 Jun 8. Proc Natl Acad Sci U S A. 2011. PMID: 21653884 Free PMC article.
962 results