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Host-microbiome interactions in human type 2 diabetes following prebiotic fibre (galacto-oligosaccharide) intake.
Pedersen C, Gallagher E, Horton F, Ellis RJ, Ijaz UZ, Wu H, Jaiyeola E, Diribe O, Duparc T, Cani PD, Gibson GR, Hinton P, Wright J, La Ragione R, Robertson MD. Pedersen C, et al. Among authors: duparc t. Br J Nutr. 2016 Dec;116(11):1869-1877. doi: 10.1017/S0007114516004086. Epub 2016 Dec 15. Br J Nutr. 2016. PMID: 27974055 Free article. Clinical Trial.
Gut microbiota, enteroendocrine functions and metabolism.
Cani PD, Everard A, Duparc T. Cani PD, et al. Among authors: duparc t. Curr Opin Pharmacol. 2013 Dec;13(6):935-40. doi: 10.1016/j.coph.2013.09.008. Epub 2013 Sep 24. Curr Opin Pharmacol. 2013. PMID: 24075718 Review.
Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism.
Duparc T, Plovier H, Marrachelli VG, Van Hul M, Essaghir A, Ståhlman M, Matamoros S, Geurts L, Pardo-Tendero MM, Druart C, Delzenne NM, Demoulin JB, van der Merwe SW, van Pelt J, Bäckhed F, Monleon D, Everard A, Cani PD. Duparc T, et al. Gut. 2017 Apr;66(4):620-632. doi: 10.1136/gutjnl-2015-310904. Epub 2016 May 5. Gut. 2017. PMID: 27196572 Free PMC article.
Intestinal epithelial MyD88 is a sensor switching host metabolism towards obesity according to nutritional status.
Everard A, Geurts L, Caesar R, Van Hul M, Matamoros S, Duparc T, Denis RG, Cochez P, Pierard F, Castel J, Bindels LB, Plovier H, Robine S, Muccioli GG, Renauld JC, Dumoutier L, Delzenne NM, Luquet S, Bäckhed F, Cani PD. Everard A, et al. Among authors: duparc t. Nat Commun. 2014 Dec 5;5:5648. doi: 10.1038/ncomms6648. Nat Commun. 2014. PMID: 25476696 Free PMC article.
Apelin targets gut contraction to control glucose metabolism via the brain.
Fournel A, Drougard A, Duparc T, Marlin A, Brierley SM, Castro J, Le-Gonidec S, Masri B, Colom A, Lucas A, Rousset P, Cenac N, Vergnolle N, Valet P, Cani PD, Knauf C. Fournel A, et al. Among authors: duparc t. Gut. 2017 Feb;66(2):258-269. doi: 10.1136/gutjnl-2015-310230. Epub 2015 Nov 12. Gut. 2017. PMID: 26565000 Free PMC article.
Central chronic apelin infusion decreases energy expenditure and thermogenesis in mice.
Drougard A, Fournel A, Marlin A, Meunier E, Abot A, Bautzova T, Duparc T, Louche K, Batut A, Lucas A, Le-Gonidec S, Lesage J, Fioramonti X, Moro C, Valet P, Cani PD, Knauf C. Drougard A, et al. Among authors: duparc t. Sci Rep. 2016 Aug 23;6:31849. doi: 10.1038/srep31849. Sci Rep. 2016. PMID: 27549402 Free PMC article.
A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice.
Plovier H, Everard A, Druart C, Depommier C, Van Hul M, Geurts L, Chilloux J, Ottman N, Duparc T, Lichtenstein L, Myridakis A, Delzenne NM, Klievink J, Bhattacharjee A, van der Ark KC, Aalvink S, Martinez LO, Dumas ME, Maiter D, Loumaye A, Hermans MP, Thissen JP, Belzer C, de Vos WM, Cani PD. Plovier H, et al. Among authors: duparc t. Nat Med. 2017 Jan;23(1):107-113. doi: 10.1038/nm.4236. Epub 2016 Nov 28. Nat Med. 2017. PMID: 27892954 Free article. Clinical Trial.
35 results