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Pharmacokinetic interaction between pyronaridine-artesunate and metoprolol.
Morris CA, Pokorny R, Lopez-Lazaro L, Miller RM, Arbe-Barnes S, Duparc S, Borghini-Fuhrer I, Shin JS, Fleckenstein L. Morris CA, et al. Among authors: duparc s. Antimicrob Agents Chemother. 2014 Oct;58(10):5900-8. doi: 10.1128/AAC.02716-14. Epub 2014 Jul 28. Antimicrob Agents Chemother. 2014. PMID: 25070091 Free PMC article. Clinical Trial.
Efficacy and safety of a fixed-dose oral combination of pyronaridine-artesunate compared with artemether-lumefantrine in children and adults with uncomplicated Plasmodium falciparum malaria: a randomised non-inferiority trial.
Tshefu AK, Gaye O, Kayentao K, Thompson R, Bhatt KM, Sesay SS, Bustos DG, Tjitra E, Bedu-Addo G, Borghini-Fuhrer I, Duparc S, Shin CS, Fleckenstein L; Pyronaridine-artesunate Study Team. Tshefu AK, et al. Among authors: duparc s. Lancet. 2010 Apr 24;375(9724):1457-67. doi: 10.1016/S0140-6736(10)60322-4. Lancet. 2010. PMID: 20417857 Clinical Trial.
Pyronaridine-artesunate versus chloroquine in patients with acute Plasmodium vivax malaria: a randomized, double-blind, non-inferiority trial.
Poravuth Y, Socheat D, Rueangweerayut R, Uthaisin C, Pyae Phyo A, Valecha N, Rao BH, Tjitra E, Purnama A, Borghini-Fuhrer I, Duparc S, Shin CS, Fleckenstein L. Poravuth Y, et al. Among authors: duparc s. PLoS One. 2011 Jan 18;6(1):e14501. doi: 10.1371/journal.pone.0014501. PLoS One. 2011. PMID: 21267072 Free PMC article. Clinical Trial.
Optimal dose finding for novel antimalarial combination therapy.
Duparc S, Lanza C, Ubben D, Borghini-Fuhrer I, Kellam L. Duparc S, et al. Trop Med Int Health. 2012 Apr;17(4):409-13. doi: 10.1111/j.1365-3156.2012.02963.x. Epub 2012 Mar 7. Trop Med Int Health. 2012. PMID: 22394082 Free PMC article.
Pyronaridine-artesunate versus mefloquine plus artesunate for malaria.
Rueangweerayut R, Phyo AP, Uthaisin C, Poravuth Y, Binh TQ, Tinto H, Pénali LK, Valecha N, Tien NT, Abdulla S, Borghini-Fuhrer I, Duparc S, Shin CS, Fleckenstein L; Pyronaridine–Artesunate Study Team. Rueangweerayut R, et al. Among authors: duparc s. N Engl J Med. 2012 Apr 5;366(14):1298-309. doi: 10.1056/NEJMoa1007125. N Engl J Med. 2012. PMID: 22475593 Free article. Clinical Trial.
First-in-man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials.
Moehrle JJ, Duparc S, Siethoff C, van Giersbergen PL, Craft JC, Arbe-Barnes S, Charman SA, Gutierrez M, Wittlin S, Vennerstrom JL. Moehrle JJ, et al. Among authors: duparc s. Br J Clin Pharmacol. 2013 Feb;75(2):524-37. doi: 10.1111/j.1365-2125.2012.04368.x. Br J Clin Pharmacol. 2013. PMID: 22759078 Free PMC article. Clinical Trial.
106 results