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Dual antibody inhibition of KLK5 and KLK7 for Netherton syndrome and atopic dermatitis.
Chavarria-Smith J, Chiu CPC, Jackman JK, Yin J, Zhang J, Hackney JA, Lin WY, Tyagi T, Sun Y, Tao J, Dunlap D, Morton WD, Ghodge SV, Maun HR, Li H, Hernandez-Barry H, Loyet KM, Chen E, Liu J, Tam C, Yaspan BL, Cai H, Balazs M, Arron JR, Li J, Wittwer AJ, Pappu R, Austin CD, Lee WP, Lazarus RA, Sudhamsu J, Koerber JT, Yi T. Chavarria-Smith J, et al. Among authors: dunlap d. Sci Transl Med. 2022 Dec 14;14(675):eabp9159. doi: 10.1126/scitranslmed.abp9159. Epub 2022 Dec 14. Sci Transl Med. 2022. PMID: 36516271
The peptide symporter SLC15a4 is essential for the development of systemic lupus erythematosus in murine models.
Katewa A, Suto E, Hui J, Heredia J, Liang J, Hackney J, Anderson K, Alcantar TM, Bacarro N, Dunlap D, Eastham J, Paler-Martinez A, Rairdan XY, Modrusan Z, Lee WP, Austin CD, Lafkas D, Ghilardi N. Katewa A, et al. Among authors: dunlap d. PLoS One. 2021 Jan 14;16(1):e0244439. doi: 10.1371/journal.pone.0244439. eCollection 2021. PLoS One. 2021. PMID: 33444326 Free PMC article.
Anti-LYPD1/CD3 T-Cell-Dependent Bispecific Antibody for the Treatment of Ovarian Cancer.
Lo AA, Johnston J, Li J, Mandikian D, Hristopoulos M, Clark R, Nickles D, Liang WC, Hötzel K, Dunlap D, Pham T, Cai H, Ovacik M, Bravo-Perez D, Mai E, Slaga D, Ellerman D, Ziai J, Totpal K, Lee G, Boswell CA, Payandeh J, Wu Y, Junttila TT. Lo AA, et al. Among authors: dunlap d. Mol Cancer Ther. 2021 Apr;20(4):716-725. doi: 10.1158/1535-7163.MCT-20-0490. Epub 2021 Feb 3. Mol Cancer Ther. 2021. PMID: 33536191
Ubiquitin ligase COP1 coordinates transcriptional programs that control cell type specification in the developing mouse brain.
Newton K, Dugger DL, Sengupta-Ghosh A, Ferrando RE, Chu F, Tao J, Lam W, Haller S, Chan S, Sa S, Dunlap D, Eastham-Anderson J, Ngu H, Hung J, French DM, Webster JD, Bolon B, Liu J, Reja R, Kummerfeld S, Chen YJ, Modrusan Z, Lewcock JW, Dixit VM. Newton K, et al. Among authors: dunlap d. Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):11244-11249. doi: 10.1073/pnas.1805033115. Epub 2018 Oct 15. Proc Natl Acad Sci U S A. 2018. PMID: 30322923 Free PMC article.
Canonical hedgehog signaling augments tumor angiogenesis by induction of VEGF-A in stromal perivascular cells.
Chen W, Tang T, Eastham-Anderson J, Dunlap D, Alicke B, Nannini M, Gould S, Yauch R, Modrusan Z, DuPree KJ, Darbonne WC, Plowman G, de Sauvage FJ, Callahan CA. Chen W, et al. Among authors: dunlap d. Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9589-94. doi: 10.1073/pnas.1017945108. Epub 2011 May 19. Proc Natl Acad Sci U S A. 2011. PMID: 21597001 Free PMC article.
Selective PROTAC-mediated degradation of SMARCA2 is efficacious in SMARCA4 mutant cancers.
Cantley J, Ye X, Rousseau E, Januario T, Hamman BD, Rose CM, Cheung TK, Hinkle T, Soto L, Quinn C, Harbin A, Bortolon E, Chen X, Haskell R, Lin E, Yu SF, Del Rosario G, Chan E, Dunlap D, Koeppen H, Martin S, Merchant M, Grimmer M, Broccatelli F, Wang J, Pizzano J, Dragovich PS, Berlin M, Yauch RL. Cantley J, et al. Among authors: dunlap d. Nat Commun. 2022 Nov 10;13(1):6814. doi: 10.1038/s41467-022-34562-5. Nat Commun. 2022. PMID: 36357397 Free PMC article.
Uranium Single Particle Analysis for Simultaneous Fluorine and Uranium Isotopic Determinations via Laser-Induced Breakdown Spectroscopy/Laser Ablation-Multicollector-Inductively Coupled Plasma-Mass Spectrometry.
Manard BT, Quarles CD Jr, Bradley VC, Spano TL, Zirakparvar NA, Ticknor BW, Dunlap DR, Cable-Dunlap P, Hexel CR, Andrews HB. Manard BT, et al. Among authors: dunlap dr. J Am Chem Soc. 2024 May 8. doi: 10.1021/jacs.4c03965. Online ahead of print. J Am Chem Soc. 2024. PMID: 38717994
205 results