Duncan RC - Search Results

1

Polyphosphate is a novel cofactor for regulation of complement by a serpin, C1 inhibitor.

Wijeyewickrema LC, Lameignere E, Hor L, Duncan RC, Shiba T, Travers RJ, Kapopara PR, Lei V, Smith SA, Kim H, Morrissey JH, Pike RN, Conway EM. Wijeyewickrema LC, et al. Among authors: duncan rc. Blood. 2016 Sep 29;128(13):1766-76. doi: 10.1182/blood-2016-02-699561. Epub 2016 Jun 23. Blood. 2016. PMID: 27338096 Free PMC article.

2

The role of the lys628 (192) residue of the complement protease, c1s, in interacting with Peptide and protein substrates.

Wijeyewickrema LC, Duncan RC, Pike RN. Wijeyewickrema LC, et al. Among authors: duncan rc. Front Immunol. 2014 Sep 17;5:444. doi: 10.3389/fimmu.2014.00444. eCollection 2014. Front Immunol. 2014. PMID: 25278939 Free PMC article.

3

The initiating proteases of the complement system: controlling the cleavage.

Duncan RC, Wijeyewickrema LC, Pike RN. Duncan RC, et al. Biochimie. 2008 Feb;90(2):387-95. doi: 10.1016/j.biochi.2007.07.023. Epub 2007 Aug 6. Biochimie. 2008. PMID: 17850949 Review.

4

Multiple domains of MASP-2, an initiating complement protease, are required for interaction with its substrate C4.

Duncan RC, Bergström F, Coetzer TH, Blom AM, Wijeyewickrema LC, Pike RN. Duncan RC, et al. Mol Immunol. 2012 Jan;49(4):593-600. doi: 10.1016/j.molimm.2011.10.006. Epub 2011 Nov 8. Mol Immunol. 2012. PMID: 22071314

5

Identification of a catalytic exosite for complement component C4 on the serine protease domain of C1s.

Duncan RC, Mohlin F, Taleski D, Coetzer TH, Huntington JA, Payne RJ, Blom AM, Pike RN, Wijeyewickrema LC. Duncan RC, et al. J Immunol. 2012 Sep 1;189(5):2365-73. doi: 10.4049/jimmunol.1201085. Epub 2012 Aug 1. J Immunol. 2012. PMID: 22855709

6

Molecular determinants of the substrate specificity of the complement-initiating protease, C1r.

Wijeyewickrema LC, Yongqing T, Tran TP, Thompson PE, Viljoen JE, Coetzer TH, Duncan RC, Kass I, Buckle AM, Pike RN. Wijeyewickrema LC, et al. Among authors: duncan rc. J Biol Chem. 2013 May 31;288(22):15571-80. doi: 10.1074/jbc.M113.451757. Epub 2013 Apr 15. J Biol Chem. 2013. PMID: 23589288 Free PMC article.

7

A molecular switch governs the interaction between the human complement protease C1s and its substrate, complement C4.

Perry AJ, Wijeyewickrema LC, Wilmann PG, Gunzburg MJ, D'Andrea L, Irving JA, Pang SS, Duncan RC, Wilce JA, Whisstock JC, Pike RN. Perry AJ, et al. Among authors: duncan rc. J Biol Chem. 2013 May 31;288(22):15821-9. doi: 10.1074/jbc.M113.464545. Epub 2013 Apr 16. J Biol Chem. 2013. PMID: 23592783 Free PMC article.

8

Mannose-binding lectin serine proteases and associated proteins of the lectin pathway of complement: two genes, five proteins and many functions?

Yongqing T, Drentin N, Duncan RC, Wijeyewickrema LC, Pike RN. Yongqing T, et al. Among authors: duncan rc. Biochim Biophys Acta. 2012 Jan;1824(1):253-62. doi: 10.1016/j.bbapap.2011.05.021. Epub 2011 Jun 6. Biochim Biophys Acta. 2012. PMID: 21664989 Review.

9

Discovery of amino acid motifs for thrombin cleavage and validation using a model substrate.

Ng NM, Pierce JD, Webb GI, Ratnikov BI, Wijeyewickrema LC, Duncan RC, Robertson AL, Bottomley SP, Boyd SE, Pike RN. Ng NM, et al. Among authors: duncan rc. Biochemistry. 2011 Dec 6;50(48):10499-507. doi: 10.1021/bi201333g. Epub 2011 Nov 11. Biochemistry. 2011. PMID: 22050556

10

Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B.

Vivian JP, Duncan RC, Berry R, O'Connor GM, Reid HH, Beddoe T, Gras S, Saunders PM, Olshina MA, Widjaja JM, Harpur CM, Lin J, Maloveste SM, Price DA, Lafont BA, McVicar DW, Clements CS, Brooks AG, Rossjohn J. Vivian JP, et al. Among authors: duncan rc. Nature. 2011 Oct 23;479(7373):401-5. doi: 10.1038/nature10517. Nature. 2011. PMID: 22020283 Free PMC article.

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