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Preclinical safety and efficacy characterization of an LpxC inhibitor against Gram-negative pathogens.
Zhao J, Cochrane CS, Najeeb J, Gooden D, Sciandra C, Fan P, Lemaitre N, Newns K, Nicholas RA, Guan Z, Thaden JT, Fowler VG Jr, Spasojevic I, Sebbane F, Toone EJ, Duncan C, Gammans R, Zhou P. Zhao J, et al. Among authors: duncan c. Sci Transl Med. 2023 Aug 9;15(708):eadf5668. doi: 10.1126/scitranslmed.adf5668. Epub 2023 Aug 9. Sci Transl Med. 2023. PMID: 37556556
SARS-CoV-2 RNA and nucleocapsid antigen are blood biomarkers associated with severe disease outcomes that improve in response to remdesivir.
Singh K, Rubenstein K, Callier V, Shaw-Saliba K, Rupert A, Dewar R, Laverdure S, Highbarger H, Lallemand P, Huang ML, Jerome KR, Sampoleo R, Mills MG, Greninger AL, Juneja K, Porter D, Benson CA, Dempsey W, El Sahly HM, Focht C, Jilg N, Paules CI, Rapaka RR, Uyeki TM, Lane HC, Beigel J, Dodd LE; Adaptive COVID-19 Treatment Trial (ACTT-1) Study Group Members. Singh K, et al. J Infect Dis. 2024 Apr 24:jiae198. doi: 10.1093/infdis/jiae198. Online ahead of print. J Infect Dis. 2024. PMID: 38657001
Social Determinants of Long-Term Opioid Use Following Total Knee Arthroplasty.
Hadlandsmyth K, Lund BC, Gao Y, Strayer AL, Davila H, Hausmann LRM, Schmidt S, Shireman PK, Jacobs MA, Mader MJ, Tessler RA, Duncan CA, Hall DE, Sarrazin MV. Hadlandsmyth K, et al. Among authors: duncan ca. J Knee Surg. 2024 Apr 10. doi: 10.1055/s-0044-1786021. Online ahead of print. J Knee Surg. 2024. PMID: 38599604
Truncating NFKB1 variants cause combined NLRP3 inflammasome activation and type I interferon signaling and predispose to necrotizing fasciitis.
Nurmi K, Silventoinen K, Keskitalo S, Rajamäki K, Kouri VP, Kinnunen M, Jalil S, Maldonado R, Wartiovaara K, Nievas EI, Denita-Juárez SP, Duncan CJA, Kuismin O, Saarela J, Romo I, Martelius T, Parantainen J, Beklen A, Bilicka M, Matikainen S, Nordström DC, Kaustio M, Wartiovaara-Kautto U, Kilpivaara O, Klein C, Hauck F, Jahkola T, Hautala T, Varjosalo M, Barreto G, Seppänen MRJ, Eklund KK. Nurmi K, et al. Among authors: duncan cja. Cell Rep Med. 2024 Apr 16;5(4):101503. doi: 10.1016/j.xcrm.2024.101503. Epub 2024 Apr 8. Cell Rep Med. 2024. PMID: 38593810 Free PMC article.
The Adverse Event Landscape of Stem Cell Transplant: Evidence for aGVHD Driving Early Transplant Associated Toxicities.
Takahashi T, Watkins B, Bratrude B, Neuberg D, Hebert K, Betz K, Yu A, Choi SW, Davis J, Duncan C, Giller R, Grimley M, Harris AC, Jacobsohn D, Lalefar N, Farhadfar N, Pulsipher MA, Shenoy S, Petrovic A, Schultz KR, Yanik GA, Blazar BR, Horan JT, Langston A, Kean LS, Qayed M. Takahashi T, et al. Among authors: duncan c. Transplant Cell Ther. 2024 Apr 6:S2666-6367(24)00317-8. doi: 10.1016/j.jtct.2024.03.030. Online ahead of print. Transplant Cell Ther. 2024. PMID: 38583802
1,867 results