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Metformin increases glucose uptake and acts renoprotectively by reducing SHIP2 activity.
Polianskyte-Prause Z, Tolvanen TA, Lindfors S, Dumont V, Van M, Wang H, Dash SN, Berg M, Naams JB, Hautala LC, Nisen H, Mirtti T, Groop PH, Wähälä K, Tienari J, Lehtonen S. Polianskyte-Prause Z, et al. Among authors: dumont v. FASEB J. 2019 Feb;33(2):2858-2869. doi: 10.1096/fj.201800529RR. Epub 2018 Oct 15. FASEB J. 2019. PMID: 30321069 Free PMC article.
Our data unravel a novel molecular mechanism by which metformin enhances glucose uptake and acts renoprotectively by reducing SHIP2 activity.-Polianskyte-Prause, Z., Tolvanen, T. A., Lindfors, S., Dumont, V., Van, M., Wang, H., Dash, S. N., Berg, M., Naams, J.-B., H …
Our data unravel a novel molecular mechanism by which metformin enhances glucose uptake and acts renoprotectively by reducing SHIP2 activity …
Cyclin-dependent kinase 2 protects podocytes from apoptosis.
Saurus P, Kuusela S, Dumont V, Lehtonen E, Fogarty CL, Lassenius MI, Forsblom C, Lehto M, Saleem MA, Groop PH, Lehtonen S. Saurus P, et al. Among authors: dumont v. Sci Rep. 2016 Feb 15;6:21664. doi: 10.1038/srep21664. Sci Rep. 2016. PMID: 26876672 Free PMC article.
PACSIN2 accelerates nephrin trafficking and is up-regulated in diabetic kidney disease.
Dumont V, Tolvanen TA, Kuusela S, Wang H, Nyman TA, Lindfors S, Tienari J, Nisen H, Suetsugu S, Plomann M, Kawachi H, Lehtonen S. Dumont V, et al. FASEB J. 2017 Sep;31(9):3978-3990. doi: 10.1096/fj.201601265R. Epub 2017 May 26. FASEB J. 2017. PMID: 28550045 Free PMC article.
The data suggest that elevated PACSIN2 expression accelerates nephrin trafficking and associates with albuminuria.-Dumont, V., Tolvanen, T. A., Kuusela, S., Wang, H., Nyman, T. A., Lindfors, S., Tienari, J., Nisen, H., Suetsugu, S., Plomann, M., Kawachi, H., Lehtone …
The data suggest that elevated PACSIN2 expression accelerates nephrin trafficking and associates with albuminuria.-Dumont, V., …
44 results