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Safeguard function of PU.1 shapes the inflammatory epigenome of neutrophils.
Fischer J, Walter C, Tönges A, Aleth H, Jordão MJC, Leddin M, Gröning V, Erdmann T, Lenz G, Roth J, Vogl T, Prinz M, Dugas M, Jacobsen ID, Rosenbauer F. Fischer J, et al. Among authors: dugas m. Nat Immunol. 2019 May;20(5):546-558. doi: 10.1038/s41590-019-0343-z. Epub 2019 Mar 25. Nat Immunol. 2019. PMID: 30911105
Basic4Cseq: an R/Bioconductor package for analyzing 4C-seq data.
Walter C, Schuetzmann D, Rosenbauer F, Dugas M. Walter C, et al. Among authors: dugas m. Bioinformatics. 2014 Nov 15;30(22):3268-9. doi: 10.1093/bioinformatics/btu497. Epub 2014 Jul 30. Bioinformatics. 2014. PMID: 25078398
Myeloid leukemia with transdifferentiation plasticity developing from T-cell progenitors.
Riemke P, Czeh M, Fischer J, Walter C, Ghani S, Zepper M, Agelopoulos K, Lettermann S, Gebhardt ML, Mah N, Weilemann A, Grau M, Gröning V, Haferlach T, Lenze D, Delwel R, Prinz M, Andrade-Navarro MA, Lenz G, Dugas M, Müller-Tidow C, Rosenbauer F. Riemke P, et al. Among authors: dugas m. EMBO J. 2016 Nov 15;35(22):2399-2416. doi: 10.15252/embj.201693927. Epub 2016 Aug 29. EMBO J. 2016. PMID: 27572462 Free PMC article.
Temporal autoregulation during human PU.1 locus SubTAD formation.
Schuetzmann D, Walter C, van Riel B, Kruse S, König T, Erdmann T, Tönges A, Bindels E, Weilemann A, Gebhard C, Wethmar K, Perrod C, Minderjahn J, Rehli M, Delwel R, Lenz G, Gröschel S, Dugas M, Rosenbauer F. Schuetzmann D, et al. Among authors: dugas m. Blood. 2018 Dec 20;132(25):2643-2655. doi: 10.1182/blood-2018-02-834721. Epub 2018 Oct 12. Blood. 2018. PMID: 30315124 Free article.
Infectious stimuli promote malignant B-cell acute lymphoblastic leukemia in the absence of AID.
Rodríguez-Hernández G, Opitz FV, Delgado P, Walter C, Álvarez-Prado ÁF, González-Herrero I, Auer F, Fischer U, Janssen S, Bartenhagen C, Raboso-Gallego J, Casado-García A, Orfao A, Blanco O, Alonso-López D, Rivas JL, Tena-Dávila SG, Müschen M, Dugas M, Criado FJG, Cenador MBG, Vicente-Dueñas C, Hauer J, Ramiro AR, Sanchez-Garcia I, Borkhardt A. Rodríguez-Hernández G, et al. Among authors: dugas m. Nat Commun. 2019 Dec 5;10(1):5563. doi: 10.1038/s41467-019-13570-y. Nat Commun. 2019. PMID: 31804490 Free PMC article.
Dexamethasone-mediated inhibition of Notch signalling blocks the interaction of leukaemia and mesenchymal stromal cells.
Ahmed HMM, Nimmagadda SC, Al-Matary YS, Fiori M, May T, Frank D, Patnana PK, Récher C, Schliemann C, Mikesch JH, Koenig T, Rosenbauer F, Hartmann W, Tuckermann J, Dührsen U, Lanying W, Dugas M, Opalka B, Lenz G, Khandanpour C. Ahmed HMM, et al. Among authors: dugas m. Br J Haematol. 2022 Feb;196(4):995-1006. doi: 10.1111/bjh.17940. Epub 2021 Nov 18. Br J Haematol. 2022. PMID: 34792186
Clinical relevance of molecular characteristics in Burkitt lymphoma differs according to age.
Burkhardt B, Michgehl U, Rohde J, Erdmann T, Berning P, Reutter K, Rohde M, Borkhardt A, Burmeister T, Dave S, Tzankov A, Dugas M, Sandmann S, Fend F, Finger J, Mueller S, Gökbuget N, Haferlach T, Kern W, Hartmann W, Klapper W, Oschlies I, Richter J, Kontny U, Lutz M, Maecker-Kolhoff B, Ott G, Rosenwald A, Siebert R, von Stackelberg A, Strahm B, Woessmann W, Zimmermann M, Zapukhlyak M, Grau M, Lenz G. Burkhardt B, et al. Among authors: dugas m. Nat Commun. 2022 Jul 6;13(1):3881. doi: 10.1038/s41467-022-31355-8. Nat Commun. 2022. PMID: 35794096 Free PMC article.
Epigenetic control over cell-intrinsic immune response antagonizes self-renewal in acute myeloid leukemia.
Felipe Fumero E, Walter C, Frenz JM, Seifert FC, Alla V, Hennig T, Angenendt L, Hartmann W, Wolf S, Serve H, Oellerich T, Lenz G, Müller-Tidow C, Schliemann C, Huber O, Dugas M, Mann M, Jayavelu AK, Mikesch JH, Arteaga MF. Felipe Fumero E, et al. Among authors: dugas m. Blood. 2024 Mar 8:blood.2023021640. doi: 10.1182/blood.2023021640. Online ahead of print. Blood. 2024. PMID: 38457355 Free article.
DNA methylation changes are a late event in acute promyelocytic leukemia and coincide with loss of transcription factor binding.
Schoofs T, Rohde C, Hebestreit K, Klein HU, Göllner S, Schulze I, Lerdrup M, Dietrich N, Agrawal-Singh S, Witten A, Stoll M, Lengfelder E, Hofmann WK, Schlenke P, Büchner T, Hansen K, Berdel WE, Rosenbauer F, Dugas M, Müller-Tidow C. Schoofs T, et al. Among authors: dugas m. Blood. 2013 Jan 3;121(1):178-87. doi: 10.1182/blood-2012-08-448860. Epub 2012 Nov 14. Blood. 2013. PMID: 23152544 Free article.
698 results