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The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin.
Galvan L, Francelle L, Gaillard MC, de Longprez L, Carrillo-de Sauvage MA, Liot G, Cambon K, Stimmer L, Luccantoni S, Flament J, Valette J, de Chaldée M, Auregan G, Guillermier M, Joséphine C, Petit F, Jan C, Jarrige M, Dufour N, Bonvento G, Humbert S, Saudou F, Hantraye P, Merienne K, Bemelmans AP, Perrier AL, Déglon N, Brouillet E. Galvan L, et al. Among authors: dufour n. Brain. 2018 May 1;141(5):1434-1454. doi: 10.1093/brain/awy057. Brain. 2018. PMID: 29534157 Free PMC article.
Dopamine determines the vulnerability of striatal neurons to the N-terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II.
Benchoua A, Trioulier Y, Diguet E, Malgorn C, Gaillard MC, Dufour N, Elalouf JM, Krajewski S, Hantraye P, Déglon N, Brouillet E. Benchoua A, et al. Among authors: dufour n. Hum Mol Genet. 2008 May 15;17(10):1446-56. doi: 10.1093/hmg/ddn033. Epub 2008 Feb 11. Hum Mol Genet. 2008. PMID: 18267960 Free PMC article.
Striatal and nigral pathology in a lentiviral rat model of Machado-Joseph disease.
Alves S, Régulier E, Nascimento-Ferreira I, Hassig R, Dufour N, Koeppen A, Carvalho AL, Simões S, de Lima MC, Brouillet E, Gould VC, Déglon N, de Almeida LP. Alves S, et al. Among authors: dufour n. Hum Mol Genet. 2008 Jul 15;17(14):2071-83. doi: 10.1093/hmg/ddn106. Epub 2008 Apr 1. Hum Mol Genet. 2008. PMID: 18385100 Free article.
Engineered lentiviral vector targeting astrocytes in vivo.
Colin A, Faideau M, Dufour N, Auregan G, Hassig R, Andrieu T, Brouillet E, Hantraye P, Bonvento G, Déglon N. Colin A, et al. Among authors: dufour n. Glia. 2009 Apr 15;57(6):667-79. doi: 10.1002/glia.20795. Glia. 2009. PMID: 18942755
Implication of the JNK pathway in a rat model of Huntington's disease.
Perrin V, Dufour N, Raoul C, Hassig R, Brouillet E, Aebischer P, Luthi-Carter R, Déglon N. Perrin V, et al. Among authors: dufour n. Exp Neurol. 2009 Jan;215(1):191-200. doi: 10.1016/j.expneurol.2008.10.008. Epub 2008 Oct 28. Exp Neurol. 2009. PMID: 19022249
Normal aging modulates the neurotoxicity of mutant huntingtin.
Diguet E, Petit F, Escartin C, Cambon K, Bizat N, Dufour N, Hantraye P, Déglon N, Brouillet E. Diguet E, et al. Among authors: dufour n. PLoS One. 2009;4(2):e4637. doi: 10.1371/journal.pone.0004637. Epub 2009 Feb 27. PLoS One. 2009. PMID: 19247483 Free PMC article.
Sustained effects of nonallele-specific Huntingtin silencing.
Drouet V, Perrin V, Hassig R, Dufour N, Auregan G, Alves S, Bonvento G, Brouillet E, Luthi-Carter R, Hantraye P, Déglon N. Drouet V, et al. Among authors: dufour n. Ann Neurol. 2009 Mar;65(3):276-85. doi: 10.1002/ana.21569. Ann Neurol. 2009. PMID: 19334076
123 results