Dufort MJ - Search Results

1

IL-6-targeted therapies to block the cytokine or its receptor drive distinct alterations in T cell function.

Speake C, Habib T, Lambert K, Hundhausen C, Lord S, Dufort MJ, Skinner SO, Hu A, Kinsman M, Jones BE, Maerz MD, Tatum M, Hocking AM, Nepom GT, Greenbaum CJ, Buckner JH. Speake C, et al. Among authors: dufort mj. JCI Insight. 2022 Nov 22;7(22):e159436. doi: 10.1172/jci.insight.159436. JCI Insight. 2022. PMID: 36282595 Free PMC article.

2

Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4⁺ T Cells in Peripheral Blood of Subjects with Type 1 Diabetes.

Cerosaletti K, Barahmand-Pour-Whitman F, Yang J, DeBerg HA, Dufort MJ, Murray SA, Israelsson E, Speake C, Gersuk VH, Eddy JA, Reijonen H, Greenbaum CJ, Kwok WW, Wambre E, Prlic M, Gottardo R, Nepom GT, Linsley PS. Cerosaletti K, et al. Among authors: dufort mj. J Immunol. 2017 Jul 1;199(1):323-335. doi: 10.4049/jimmunol.1700172. Epub 2017 May 31. J Immunol. 2017. PMID: 28566371 Free PMC article.

3

Elevated T cell levels in peripheral blood predict poor clinical response following rituximab treatment in new-onset type 1 diabetes.

Linsley PS, Greenbaum CJ, Rosasco M, Presnell S, Herold KC, Dufort MJ. Linsley PS, et al. Among authors: dufort mj. Genes Immun. 2019 Apr;20(4):293-307. doi: 10.1038/s41435-018-0032-1. Epub 2018 Jun 21. Genes Immun. 2019. PMID: 29925930 Free PMC article. Clinical Trial.

4

Abnormal neutrophil signature in the blood and pancreas of presymptomatic and symptomatic type 1 diabetes.

Vecchio F, Lo Buono N, Stabilini A, Nigi L, Dufort MJ, Geyer S, Rancoita PM, Cugnata F, Mandelli A, Valle A, Leete P, Mancarella F, Linsley PS, Krogvold L, Herold KC, Elding Larsson H, Richardson SJ, Morgan NG, Dahl-Jørgensen K, Sebastiani G, Dotta F, Bosi E; DRI_Biorepository Group; Type 1 Diabetes TrialNet Study Group; Battaglia M. Vecchio F, et al. Among authors: dufort mj. JCI Insight. 2018 Sep 20;3(18):e122146. doi: 10.1172/jci.insight.122146. eCollection 2018 Sep 20. JCI Insight. 2018. PMID: 30232284 Free PMC article.

5

Cell type-specific immune phenotypes predict loss of insulin secretion in new-onset type 1 diabetes.

Dufort MJ, Greenbaum CJ, Speake C, Linsley PS. Dufort MJ, et al. JCI Insight. 2019 Feb 21;4(4):e125556. doi: 10.1172/jci.insight.125556. eCollection 2019 Feb 21. JCI Insight. 2019. PMID: 30830868 Free PMC article.

6

B lymphocyte alterations accompany abatacept resistance in new-onset type 1 diabetes.

Linsley PS, Greenbaum CJ, Speake C, Long SA, Dufort MJ. Linsley PS, et al. Among authors: dufort mj. JCI Insight. 2019 Feb 21;4(4):e126136. doi: 10.1172/jci.insight.126136. eCollection 2019 Feb 21. JCI Insight. 2019. PMID: 30830871 Free PMC article.

7

A composite immune signature parallels disease progression across T1D subjects.

Speake C, Skinner SO, Berel D, Whalen E, Dufort MJ, Young WC, Odegard JM, Pesenacker AM, Gorus FK, James EA, Levings MK, Linsley PS, Akirav EM, Pugliese A, Hessner MJ, Nepom GT, Gottardo R, Long SA. Speake C, et al. Among authors: dufort mj. JCI Insight. 2019 Dec 5;4(23):e126917. doi: 10.1172/jci.insight.126917. JCI Insight. 2019. PMID: 31671072 Free PMC article.

8

Autoreactive CD8+ T cell exhaustion distinguishes subjects with slow type 1 diabetes progression.

Wiedeman AE, Muir VS, Rosasco MG, DeBerg HA, Presnell S, Haas B, Dufort MJ, Speake C, Greenbaum CJ, Serti E, Nepom GT, Blahnik G, Kus AM, James EA, Linsley PS, Long SA. Wiedeman AE, et al. Among authors: dufort mj. J Clin Invest. 2020 Jan 2;130(1):480-490. doi: 10.1172/JCI126595. J Clin Invest. 2020. PMID: 31815738 Free PMC article.

9

Innate immune stimulation of whole blood reveals IFN-1 hyper-responsiveness in type 1 diabetes.

Rodrigues KB, Dufort MJ, Llibre A, Speake C, Rahman MJ, Bondet V, Quiel J, Linsley PS, Greenbaum CJ, Duffy D, Tarbell KV. Rodrigues KB, et al. Among authors: dufort mj. Diabetologia. 2020 Aug;63(8):1576-1587. doi: 10.1007/s00125-020-05179-4. Epub 2020 Jun 5. Diabetologia. 2020. PMID: 32500289 Free PMC article.

10

Lupus IgA1 autoantibodies synergize with IgG to enhance pDC responses to RNA-containing immune complexes.

Waterman HR, Dufort MJ, Posso SE, Ni M, Li LZ, Zhu C, Raj P, Smith KD, Buckner JH, Hamerman JA. Waterman HR, et al. Among authors: dufort mj. bioRxiv [Preprint]. 2024 Apr 4:2023.09.07.556743. doi: 10.1101/2023.09.07.556743. bioRxiv. 2024. PMID: 37745328 Free PMC article. Preprint.

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