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Extracellular clusterin limits the uptake of α-synuclein fibrils by murine and human astrocytes.
Filippini A, Mutti V, Faustini G, Longhena F, Ramazzina I, Rizzi F, Kaganovich A, Roosen DA, Landeck N, Duffy M, Tessari I, Bono F, Fiorentini C, Greggio E, Bubacco L, Bellucci A, Missale M, Cookson MR, Gennarelli M, Russo I. Filippini A, et al. Among authors: duffy m. Glia. 2021 Mar;69(3):681-696. doi: 10.1002/glia.23920. Epub 2020 Oct 12. Glia. 2021. PMID: 33045109 Free PMC article.
Time course and magnitude of alpha-synuclein inclusion formation and nigrostriatal degeneration in the rat model of synucleinopathy triggered by intrastriatal α-synuclein preformed fibrils.
Patterson JR, Duffy MF, Kemp CJ, Howe JW, Collier TJ, Stoll AC, Miller KM, Patel P, Levine N, Moore DJ, Luk KC, Fleming SM, Kanaan NM, Paumier KL, El-Agnaf OMA, Sortwell CE. Patterson JR, et al. Among authors: duffy mf. Neurobiol Dis. 2019 Oct;130:104525. doi: 10.1016/j.nbd.2019.104525. Epub 2019 Jul 2. Neurobiol Dis. 2019. PMID: 31276792 Free PMC article.
Preformed fibrils generated from mouse alpha-synuclein produce more inclusion pathology in rats than fibrils generated from rat alpha-synuclein.
Howe JW, Sortwell CE, Duffy MF, Kemp CJ, Russell CP, Kubik M, Patel P, Luk KC, El-Agnaf OMA, Patterson JR. Howe JW, et al. Among authors: duffy mf. Parkinsonism Relat Disord. 2021 Aug;89:41-47. doi: 10.1016/j.parkreldis.2021.06.010. Epub 2021 Jun 19. Parkinsonism Relat Disord. 2021. PMID: 34218047 Free PMC article.
1,142 results