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Elevated circulating follistatin associates with an increased risk of type 2 diabetes.
Wu C, Borné Y, Gao R, López Rodriguez M, Roell WC, Wilson JM, Regmi A, Luan C, Aly DM, Peter A, Machann J, Staiger H, Fritsche A, Birkenfeld AL, Tao R, Wagner R, Canouil M, Hong MG, Schwenk JM, Ahlqvist E, Kaikkonen MU, Nilsson P, Shore AC, Khan F, Natali A, Melander O, Orho-Melander M, Nilsson J, Häring HU, Renström E, Wollheim CB, Engström G, Weng J, Pearson ER, Franks PW, White MF, Duffin KL, Vaag AA, Laakso M, Stefan N, Groop L, De Marinis Y. Wu C, et al. Among authors: duffin kl. Nat Commun. 2021 Nov 10;12(1):6486. doi: 10.1038/s41467-021-26536-w. Nat Commun. 2021. PMID: 34759311 Free PMC article.
The dual glucose-dependent insulinotropic peptide and glucagon-like peptide-1 receptor agonist, tirzepatide, improves lipoprotein biomarkers associated with insulin resistance and cardiovascular risk in patients with type 2 diabetes.
Wilson JM, Nikooienejad A, Robins DA, Roell WC, Riesmeyer JS, Haupt A, Duffin KL, Taskinen MR, Ruotolo G. Wilson JM, et al. Among authors: duffin kl. Diabetes Obes Metab. 2020 Dec;22(12):2451-2459. doi: 10.1111/dom.14174. Epub 2020 Sep 15. Diabetes Obes Metab. 2020. PMID: 33462955 Free PMC article. Clinical Trial.
A signature of circulating inflammatory proteins and development of end-stage renal disease in diabetes.
Niewczas MA, Pavkov ME, Skupien J, Smiles A, Md Dom ZI, Wilson JM, Park J, Nair V, Schlafly A, Saulnier PJ, Satake E, Simeone CA, Shah H, Qiu C, Looker HC, Fiorina P, Ware CF, Sun JK, Doria A, Kretzler M, Susztak K, Duffin KL, Nelson RG, Krolewski AS. Niewczas MA, et al. Among authors: duffin kl. Nat Med. 2019 May;25(5):805-813. doi: 10.1038/s41591-019-0415-5. Epub 2019 Apr 22. Nat Med. 2019. PMID: 31011203 Free PMC article.
Circulating proteins protect against renal decline and progression to end-stage renal disease in patients with diabetes.
Md Dom ZI, Satake E, Skupien J, Krolewski B, O'Neil K, Willency JA, Dillon ST, Wilson JM, Kobayashi H, Ihara K, Libermann TA, Pragnell M, Duffin KL, Krolewski AS. Md Dom ZI, et al. Among authors: duffin kl. Sci Transl Med. 2021 Jun 30;13(600):eabd2699. doi: 10.1126/scitranslmed.abd2699. Sci Transl Med. 2021. PMID: 34193611 Free PMC article.
The dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist tirzepatide improves cardiovascular risk biomarkers in patients with type 2 diabetes: A post hoc analysis.
Wilson JM, Lin Y, Luo MJ, Considine G, Cox AL, Bowsman LM, Robins DA, Haupt A, Duffin KL, Ruotolo G. Wilson JM, et al. Among authors: duffin kl. Diabetes Obes Metab. 2022 Jan;24(1):148-153. doi: 10.1111/dom.14553. Epub 2021 Oct 11. Diabetes Obes Metab. 2022. PMID: 34542221 Free PMC article. Clinical Trial.
Comprehensive Search for Novel Circulating miRNAs and Axon Guidance Pathway Proteins Associated with Risk of ESKD in Diabetes.
Satake E, Saulnier PJ, Kobayashi H, Gupta MK, Looker HC, Wilson JM, Md Dom ZI, Ihara K, O'Neil K, Krolewski B, Pipino C, Pavkov ME, Nair V, Bitzer M, Niewczas MA, Kretzler M, Mauer M, Doria A, Najafian B, Kulkarni RN, Duffin KL, Pezzolesi MG, Kahn CR, Nelson RG, Krolewski AS. Satake E, et al. Among authors: duffin kl. J Am Soc Nephrol. 2021 Sep;32(9):2331-2351. doi: 10.1681/ASN.2021010105. Epub 2021 Jun 17. J Am Soc Nephrol. 2021. PMID: 34140396 Free PMC article.
Neuroblastoma suppressor of tumorigenicity 1 is a circulating protein associated with progression to end-stage kidney disease in diabetes.
Kobayashi H, Looker HC, Satake E, D'Addio F, Wilson JM, Saulnier PJ, Md Dom ZI, O'Neil K, Ihara K, Krolewski B, Badger HS, Petrazzuolo A, Corradi D, Galecki A, Wilson PC, Najafian B, Mauer M, Niewczas MA, Doria A, Humphreys BD, Duffin KL, Fiorina P, Nelson RG, Krolewski AS. Kobayashi H, et al. Among authors: duffin kl. Sci Transl Med. 2022 Aug 10;14(657):eabj2109. doi: 10.1126/scitranslmed.abj2109. Epub 2022 Aug 10. Sci Transl Med. 2022. PMID: 35947673 Free PMC article.
86 results