Duff K - Search Results

1

Preclinical evaluation of a microtubule PET ligand [¹¹C]MPC-6827 in tau and amyotrophic lateral sclerosis animal models.

Kumar JSD, Molotkov A, Kim J, Carberry P, Idumonyi S, Castrillon J, Duff K, Shneider NA, Mintz A. Kumar JSD, et al. Among authors: duff k. Pharmacol Rep. 2022 Jun;74(3):539-544. doi: 10.1007/s43440-022-00359-y. Epub 2022 Mar 14. Pharmacol Rep. 2022. PMID: 35286710

2

Focused ultrasound mitigates pathology and improves spatial memory in Alzheimer's mice and patients.

Karakatsani ME, Ji R, Murillo MF, Kugelman T, Kwon N, Lao YH, Liu K, Pouliopoulos AN, Honig LS, Duff KE, Konofagou EE. Karakatsani ME, et al. Among authors: duff ke. Theranostics. 2023 Jul 14;13(12):4102-4120. doi: 10.7150/thno.79898. eCollection 2023. Theranostics. 2023. PMID: 37554284 Free PMC article.

3

Is tau aggregation toxic or protective?

Congdon EE, Duff KE. Congdon EE, et al. J Alzheimers Dis. 2008 Aug;14(4):453-7. doi: 10.3233/jad-2008-14415. J Alzheimers Dis. 2008. PMID: 18688098 Review.

4

Anesthesia-induced hyperphosphorylation detaches 3-repeat tau from microtubules without affecting their stability in vivo.

Planel E, Krishnamurthy P, Miyasaka T, Liu L, Herman M, Kumar A, Bretteville A, Figueroa HY, Yu WH, Whittington RA, Davies P, Takashima A, Nixon RA, Duff KE. Planel E, et al. J Neurosci. 2008 Nov 26;28(48):12798-807. doi: 10.1523/JNEUROSCI.4101-08.2008. J Neurosci. 2008. PMID: 19036972 Free PMC article.

5

Comparative lipidomic analysis of mouse and human brain with Alzheimer disease.

Chan RB, Oliveira TG, Cortes EP, Honig LS, Duff KE, Small SA, Wenk MR, Shui G, Di Paolo G. Chan RB, et al. J Biol Chem. 2012 Jan 20;287(4):2678-88. doi: 10.1074/jbc.M111.274142. Epub 2011 Dec 1. J Biol Chem. 2012. PMID: 22134919 Free PMC article.

6

3D Visualization of the Temporal and Spatial Spread of Tau Pathology Reveals Extensive Sites of Tau Accumulation Associated with Neuronal Loss and Recognition Memory Deficit in Aged Tau Transgenic Mice.

Fu H, Hussaini SA, Wegmann S, Profaci C, Daniels JD, Herman M, Emrani S, Figueroa HY, Hyman BT, Davies P, Duff KE. Fu H, et al. PLoS One. 2016 Jul 28;11(7):e0159463. doi: 10.1371/journal.pone.0159463. eCollection 2016. PLoS One. 2016. PMID: 27466814 Free PMC article.

7

Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction, and Spatial Memory Deficits Reminiscent of Early Alzheimer's Disease.

Fu H, Rodriguez GA, Herman M, Emrani S, Nahmani E, Barrett G, Figueroa HY, Goldberg E, Hussaini SA, Duff KE. Fu H, et al. Neuron. 2017 Feb 8;93(3):533-541.e5. doi: 10.1016/j.neuron.2016.12.023. Epub 2017 Jan 19. Neuron. 2017. PMID: 28111080 Free PMC article.

8

Unilateral Focused Ultrasound-Induced Blood-Brain Barrier Opening Reduces Phosphorylated Tau from The rTg4510 Mouse Model.

Karakatsani ME, Kugelman T, Ji R, Murillo M, Wang S, Niimi Y, Small SA, Duff KE, Konofagou EE. Karakatsani ME, et al. Theranostics. 2019 Jul 13;9(18):5396-5411. doi: 10.7150/thno.28717. eCollection 2019. Theranostics. 2019. PMID: 31410223 Free PMC article.

9

Atrophy associated with tau pathology precedes overt cell death in a mouse model of progressive tauopathy.

Fung CW, Guo J, Fu H, Figueroa HY, Konofagou EE, Duff KE. Fung CW, et al. Sci Adv. 2020 Oct 16;6(42):eabc8098. doi: 10.1126/sciadv.abc8098. Print 2020 Oct. Sci Adv. 2020. PMID: 33067235 Free PMC article.

10

PAC1 receptor-mediated clearance of tau in postsynaptic compartments attenuates tau pathology in mouse brain.

Schaler AW, Runyan AM, Clelland CL, Sydney EJ, Fowler SL, Figueroa HY, Shioda S, Santa-Maria I, Duff KE, Myeku N. Schaler AW, et al. Sci Transl Med. 2021 May 26;13(595):eaba7394. doi: 10.1126/scitranslmed.aba7394. Sci Transl Med. 2021. PMID: 34039738 Free PMC article.

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