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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, Abela GS, Franchi L, Nuñez G, Schnurr M, Espevik T, Lien E, Fitzgerald KA, Rock KL, Moore KJ, Wright SD, Hornung V, Latz E. Duewell P, et al. Nature. 2010 Apr 29;464(7293):1357-61. doi: 10.1038/nature08938. Nature. 2010. PMID: 20428172 Free PMC article.
NLRP3 inflammasome activation in inflammaging.
Latz E, Duewell P. Latz E, et al. Among authors: duewell p. Semin Immunol. 2018 Dec;40:61-73. doi: 10.1016/j.smim.2018.09.001. Epub 2018 Sep 26. Semin Immunol. 2018. PMID: 30268598 Review.
Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming.
Christ A, Günther P, Lauterbach MAR, Duewell P, Biswas D, Pelka K, Scholz CJ, Oosting M, Haendler K, Baßler K, Klee K, Schulte-Schrepping J, Ulas T, Moorlag SJCFM, Kumar V, Park MH, Joosten LAB, Groh LA, Riksen NP, Espevik T, Schlitzer A, Li Y, Fitzgerald ML, Netea MG, Schultze JL, Latz E. Christ A, et al. Among authors: duewell p. Cell. 2018 Jan 11;172(1-2):162-175.e14. doi: 10.1016/j.cell.2017.12.013. Cell. 2018. PMID: 29328911 Free PMC article.
Nlrp3-dependent IL-1β inhibits CD103+ dendritic cell differentiation in the gut.
Mak'Anyengo R, Duewell P, Reichl C, Hörth C, Lehr HA, Fischer S, Clavel T, Denk G, Hohenester S, Kobold S, Endres S, Schnurr M, Bauer C. Mak'Anyengo R, et al. Among authors: duewell p. JCI Insight. 2018 Mar 8;3(5):e96322. doi: 10.1172/jci.insight.96322. JCI Insight. 2018. PMID: 29515025 Free PMC article.
35 results