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Engineering of the Saccharomyces cerevisiae yeast strain with multiple chromosome-integrated genes of human alpha-fetoprotein and its high-yield secretory production, purification, structural and functional characterization.
Dudich E, Dudich I, Semenkova L, Benevolensky S, Morozkina E, Marchenko A, Zatcepin S, Dudich D, Soboleva G, Khromikh L, Roslovtceva O, Tatulov E. Dudich E, et al. Protein Expr Purif. 2012 Jul;84(1):94-107. doi: 10.1016/j.pep.2012.04.008. Epub 2012 Apr 26. Protein Expr Purif. 2012. PMID: 22561245
Isolation and structural and functional characterization of two stable peptic fragments of human alpha-fetoprotein.
Dudich I, Tokhtamysheva N, Semenkova L, Dudich E, Hellman J, Korpela T. Dudich I, et al. Among authors: dudich e. Biochemistry. 1999 Aug 10;38(32):10406-14. doi: 10.1021/bi990630h. Biochemistry. 1999. PMID: 10441135
Tumor-suppressive activity via induction of apoptosis was recently shown for AFP [Dudich, E. I., et al. (1998) Tumor Biol. 19, 261-272]. We studied here the ability of isolated proteolytic AFP fragments to induce apoptosis in the AFP-sensitive Raji cell line, to det …
Tumor-suppressive activity via induction of apoptosis was recently shown for AFP [Dudich, E. I., et al. (1998) Tumor Biol. 19, …
30 results