Dudek NL - Search Results

1

Perturbations in nuclear factor-kappaB or c-Jun N-terminal kinase pathways in pancreatic beta cells confer susceptibility to cytokine-induced cell death.

Thomas HE, Angstetra E, Fernandes RV, Mariana L, Irawaty W, Jamieson EL, Dudek NL, Kay TW. Thomas HE, et al. Among authors: dudek nl. Immunol Cell Biol. 2006 Feb;84(1):20-7. doi: 10.1111/j.1440-1711.2005.01397.x. Epub 2005 Nov 7. Immunol Cell Biol. 2006. PMID: 16277639

2

Suppressor of cytokine signaling-1 overexpression protects pancreatic beta cells from CD8+ T cell-mediated autoimmune destruction.

Chong MM, Chen Y, Darwiche R, Dudek NL, Irawaty W, Santamaria P, Allison J, Kay TW, Thomas HE. Chong MM, et al. Among authors: dudek nl. J Immunol. 2004 May 1;172(9):5714-21. doi: 10.4049/jimmunol.172.9.5714. J Immunol. 2004. PMID: 15100317

3

Perforin and Fas induced by IFNgamma and TNFalpha mediate beta cell death by OT-I CTL.

McKenzie MD, Dudek NL, Mariana L, Chong MM, Trapani JA, Kay TW, Thomas HE. McKenzie MD, et al. Among authors: dudek nl. Int Immunol. 2006 Jun;18(6):837-46. doi: 10.1093/intimm/dxl020. Epub 2006 Mar 30. Int Immunol. 2006. PMID: 16574667

4

Cytotoxic T-cells from T-cell receptor transgenic NOD8.3 mice destroy beta-cells via the perforin and Fas pathways.

Dudek NL, Thomas HE, Mariana L, Sutherland RM, Allison J, Estella E, Angstetra E, Trapani JA, Santamaria P, Lew AM, Kay TW. Dudek NL, et al. Diabetes. 2006 Sep;55(9):2412-8. doi: 10.2337/db06-0109. Diabetes. 2006. PMID: 16936188

5

Cytotoxic T-lymphocyte-mediated killing of human pancreatic islet cells in vitro.

Campbell PD, Estella E, Dudek NL, Jhala G, Thomas HE, Kay TW, Mannering SI. Campbell PD, et al. Among authors: dudek nl. Hum Immunol. 2008 Sep;69(9):543-51. doi: 10.1016/j.humimm.2008.06.008. Epub 2008 Jul 17. Hum Immunol. 2008. PMID: 18639598

6

In vivo effects of cytokines on pancreatic beta-cells in models of type I diabetes dependent on CD4(+) T lymphocytes.

Angstetra E, Graham KL, Emmett S, Dudek NL, Darwiche R, Ayala-Perez R, Allison J, Santamaria P, Kay TW, Thomas HE. Angstetra E, et al. Among authors: dudek nl. Immunol Cell Biol. 2009 Feb;87(2):178-85. doi: 10.1038/icb.2008.81. Epub 2008 Nov 18. Immunol Cell Biol. 2009. PMID: 19015667

7

Interferon signalling in pancreatic beta cells.

Thomas HE, Graham KL, Angstetra E, McKenzie MD, Dudek NL, Kay TW. Thomas HE, et al. Among authors: dudek nl. Front Biosci (Landmark Ed). 2009 Jan 1;14(2):644-56. doi: 10.2741/3270. Front Biosci (Landmark Ed). 2009. PMID: 19273092 Free article. Review.

8

Cytotoxic T cell mechanisms of beta cell destruction in non-obese diabetic mice.

Kay TW, Dudek NL, Graham K, Estella E, Angstetra E, McKenzie MD, Allison J, Thomas HE. Kay TW, et al. Among authors: dudek nl. Novartis Found Symp. 2008;292:68-78; discussion 78-84, 122-9, 202-3. doi: 10.1002/9780470697405.ch6. Novartis Found Symp. 2008. PMID: 19203093

9

Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP.

Krishnamurthy B, Dudek NL, McKenzie MD, Purcell AW, Brooks AG, Gellert S, Colman PG, Harrison LC, Lew AM, Thomas HE, Kay TW. Krishnamurthy B, et al. Among authors: dudek nl. J Clin Invest. 2006 Dec;116(12):3258-65. doi: 10.1172/JCI29602. J Clin Invest. 2006. PMID: 17143333 Free PMC article.

10

Proinsulin-specific, HLA-DQ8, and HLA-DQ8-transdimer-restricted CD4+ T cells infiltrate islets in type 1 diabetes.

Pathiraja V, Kuehlich JP, Campbell PD, Krishnamurthy B, Loudovaris T, Coates PT, Brodnicki TC, O'Connell PJ, Kedzierska K, Rodda C, Bergman P, Hill E, Purcell AW, Dudek NL, Thomas HE, Kay TW, Mannering SI. Pathiraja V, et al. Among authors: dudek nl. Diabetes. 2015 Jan;64(1):172-82. doi: 10.2337/db14-0858. Epub 2014 Aug 25. Diabetes. 2015. PMID: 25157096

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