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A RAD51 assay feasible in routine tumor samples calls PARP inhibitor response beyond BRCA mutation.
EMBO Mol Med. 2018 Dec;10(12):e9172. doi: 10.15252/emmm.201809172.
EMBO Mol Med. 2018.
PMID: 30377213
Free PMC article.
A global functional analysis of missense mutations reveals two major hotspots in the PALB2 tumor suppressor.
Rodrigue A, Margaillan G, Torres Gomes T, Coulombe Y, Montalban G, da Costa E Silva Carvalho S, Milano L, Ducy M, De-Gregoriis G, Dellaire G, Araújo da Silva W Jr, Monteiro AN, Carvalho MA, Simard J, Masson JY.
Rodrigue A, et al. Among authors: ducy m.
Nucleic Acids Res. 2019 Nov 18;47(20):10662-10677. doi: 10.1093/nar/gkz780.
Nucleic Acids Res. 2019.
PMID: 31586400
Free PMC article.
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Functional characterization of 84 PALB2 variants of uncertain significance.
Wiltshire T, Ducy M, Foo TK, Hu C, Lee KY, Belur Nagaraj A, Rodrigue A, Gomes TT, Simard J, Monteiro ANA, Xia B, Carvalho MA, Masson JY, Couch FJ.
Wiltshire T, et al. Among authors: ducy m.
Genet Med. 2020 Mar;22(3):622-632. doi: 10.1038/s41436-019-0682-z. Epub 2019 Oct 21.
Genet Med. 2020.
PMID: 31636395
Free PMC article.
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The Tumor Suppressor PALB2: Inside Out.
Ducy M, Sesma-Sanz L, Guitton-Sert L, Lashgari A, Gao Y, Brahiti N, Rodrigue A, Margaillan G, Caron MC, Côté J, Simard J, Masson JY.
Ducy M, et al.
Trends Biochem Sci. 2019 Mar;44(3):226-240. doi: 10.1016/j.tibs.2018.10.008. Epub 2019 Jan 10.
Trends Biochem Sci. 2019.
PMID: 30638972
Review.
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