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The naturally processed CD95L elicits a c-yes/calcium/PI3K-driven cell migration pathway.
Tauzin S, Chaigne-Delalande B, Selva E, Khadra N, Daburon S, Contin-Bordes C, Blanco P, Le Seyec J, Ducret T, Counillon L, Moreau JF, Hofman P, Vacher P, Legembre P. Tauzin S, et al. Among authors: ducret t. PLoS Biol. 2011 Jun;9(6):e1001090. doi: 10.1371/journal.pbio.1001090. Epub 2011 Jun 21. PLoS Biol. 2011. PMID: 21713032 Free PMC article.
CD95 triggers Orai1-mediated localized Ca2+ entry, regulates recruitment of protein kinase C (PKC) β2, and prevents death-inducing signaling complex formation.
Khadra N, Bresson-Bepoldin L, Penna A, Chaigne-Delalande B, Ségui B, Levade T, Vacher AM, Reiffers J, Ducret T, Moreau JF, Cahalan MD, Vacher P, Legembre P. Khadra N, et al. Among authors: ducret t. Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):19072-7. doi: 10.1073/pnas.1116946108. Epub 2011 Nov 7. Proc Natl Acad Sci U S A. 2011. PMID: 22065776 Free PMC article.
The apoptotic members CD95, BclxL, and Bcl-2 cooperate to promote cell migration by inducing Ca(2+) flux from the endoplasmic reticulum to mitochondria.
Fouqué A, Lepvrier E, Debure L, Gouriou Y, Malleter M, Delcroix V, Ovize M, Ducret T, Li C, Hammadi M, Vacher P, Legembre P. Fouqué A, et al. Among authors: ducret t. Cell Death Differ. 2016 Oct;23(10):1702-16. doi: 10.1038/cdd.2016.61. Epub 2016 Jul 1. Cell Death Differ. 2016. PMID: 27367565 Free PMC article.
63 results